Evidence map›Paper›PMID 34476863›Full record

ArticleNMR in biomedicine2021

Automated segmentation of biventricular contours in tissue phase mapping using deep learning.

Daming Shen, Ashitha Pathrose, Roberto Sarnari, Allison Blake, Haben Berhane, Justin J Baraboo, James C Carr, Michael Markl, Daniel Kim

Abstract read
In one paragraph

Article in NMR in biomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Daming ShenDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-4706-8566
Ashitha PathroseDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-1761-0780
Roberto SarnariDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Allison BlakeDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Haben BerhaneDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Justin J BarabooDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
James C CarrDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Michael MarklDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.
Daniel KimDepartment of Radiology, Northwestern University Feinberg School of Medicine, Chicago, Illinois, USA.ORCID 0000-0003-2660-8973

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Comprehensive Cardiac Structure-Function Analysis in Heart TransplantationR01HL117888 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI CARR, JAMES, MARKL, MICHAEL · 2014 to 2025
$6.4M
Precision MRI of Left Atrial Fibrosis for Patients with Atrial FibrillationR01HL116895 · NHLBI · UNIVERSITY OF UTAH · PI KIM, DANIEL · 2014 to 2025
$5.1M
Wideband 3D LGE and Coronary MRA for Planning Ventricular Tachycardia AblationR01HL151079 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Daniel Kim, Daniel Ching-Hao Lee · 2020 to 2026
$4.0M
Graduate Training Program for Magnetic Resonance ImagingT32EB025766 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI Michael Markl · 2019 to 2026
$1.6M
Rapid Real-Time Cardiovascular MRI for Detecting Coronary Artery DiseaseR01HL138578 · NHLBI · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL, LEE, DANIEL CHING-HAO · 2017 to 2019
$1.1M
Rapid Pediatric Cardiovascular MRI without Contrast Agent or AnesthesiaR21EB024315 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL · 2017 to 2018
$567k
MRI of Left Atrial Hemodynamic Disorders in Atrial FibrillationR21AG055954 · NIA · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KIM, DANIEL, MARKL, MICHAEL · 2017 to 2018
$487k
Next-Generation Cardiovascular MRI powered by Artificial IntelligenceR21EB030806 · NIBIB · NORTHWESTERN UNIVERSITY AT CHICAGO · PI KATSAGGELOS, AGGELOS K, KIM, DANIEL · 2021 to 2022
$420k
NCATS NIH HHS UL1 TR001422NHLBI NIH HHS R01 HL116895NHLBI NIH HHS R01 HL117888NHLBI NIH HHS R01 HL138578NHLBI NIH HHS R01 HL151079NIA NIH HHS R21 AG055954NIBIB NIH HHS R21 EB024315NIBIB NIH HHS R21 EB030806NIBIB NIH HHS T32 EB025766
6 · The paper itself

Abstract

Tissue phase mapping (TPM) is an MRI technique for quantification of regional biventricular myocardial velocities. Despite its potential, clinical use is limited due to the requisite labor-intensive manual segmentation of cardiac contours for all time frames. The purpose of this study was to develop a deep learning (DL) network for automated segmentation of TPM images, without significant loss in segmentation and myocardial velocity quantification accuracy compared with manual segmentation. We implemented a multi-channel 3D (three dimensional; 2D + time) dense U-Net that trained on magnitude and phase images and combined cross-entropy, Dice, and Hausdorff distance loss terms to improve the segmentation accuracy and suppress unnatural boundaries. The dense U-Net was trained and tested with 150 multi-slice, multi-phase TPM scans (114 scans for training, 36 for testing) from 99 heart transplant patients (44 females, 1-4 scans/patient), where the magnitude and velocity-encoded (V

Indexed as

Deep LearningAdultAgedFemaleHeart TransplantationHeart VentriclesHumansMagnetic Resonance Imaging, CineMaleMiddle Ageddeep learning (DL)image segmentationmulti-channel 3D dense U-Nettissue phase mapping (TPM)

Identifiers

PMID34476863
PMCPMC8795858

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.