SynthesisSleep & breathing = Schlaf & Atmung2022
Nasal function and CPAP use in patients with obstructive sleep apnoea: a systematic review.
Synthesis in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 20 citations in OpenAlex.
- The efficiency of azelastine hydrochloride and fluticasone propionate nasal spray to improve PAP adherence in patients with obstructive sleep apnea.Scientific reports · 2025Trial
- Healthcare Resource Utilization and Cost After Temperature-Controlled Radiofrequency Treatment of Nasal Airway Obstruction: A Real-World Longitudinal Claims Analysis.International forum of allergy & rhinology · 2026Article
- The role of nasal patency in obstructive sleep apnea: an expert consensus.Frontiers in sleep · 2026Article
- Measuring Nasal Airway Resistance to Personalize Surgery for Nasal Obstruction in OSA Patients.Journal of personalized medicine · 2025Article
- Comprehensive Management of Obstructive Sleep Apnea With CPAP in a Surgical Otolaryngology Practice.The Laryngoscope · 2025Article
- The impact of resident involvement and postgraduate year on head and neck surgery for obstructive sleep apnea.PloS one · 2025Article
- Role of Nasal Surgery in Adult Obstructive Sleep Apnea: A Systematic Review.Sleep science (Sao Paulo, Brazil) · 2024Review
- Air leak phenotyping by mandibular jaw movement analysis in CPAP therapy: Key insights for practitioners.Respirology case reports · 2024Article
- Editorial on the Special Issue "Obstructive Sleep Apnea (OSA)".Life (Basel, Switzerland) · 2024Article
- Diagnosis and management of obstructive sleep apnoea in adults.Australian prescriber · 2024Review
- Association between nasal airway minimal cross-sectional areas and obstructive sleep apnoea.European journal of orthodontics · 2023Article
- Monitoring Seasonal Compliance of Patients with Obstructive Sleep Apnea Using CPAP Systems via SD Card.Acta informatica medica : AIM : journal of the Society for Medical Informatics of Bosnia & Herzegovina : casopis Drustva za medicinsku informatiku BiH · 2023Article
- The Role of Inverted Papilloma Surgical Removal for Sleep Apnea Treatment Success-A Case Report.Medicina (Kaunas, Lithuania) · 2023Article
- Outcome of Continuous Positive Airway Pressure Adherence Based on Nasal Endoscopy and the Measurement of Nasal Patency-A Prospective Study.Life (Basel, Switzerland) · 2023Article
- Nasal Symptoms in Patients with Obstructive Sleep Apnoea and Their Association with Continuous Positive Airway Pressure Usage.Life (Basel, Switzerland) · 2022Article
- Brazilian Thoracic Association Consensus on Sleep-disordered Breathing.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2022Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis systematic review was conducted to answer the following 3 questions: 'Does nasal pathology affect CPAP use?', 'What is the effect of CPAP on the nose?' and 'Does treatment of nasal pathology affect CPAP use?'.
methodsPubmed and Scopus databases were searched for articles relevant to the study questions up to October 2020.
resultsSixty-three articles were selected, of which a majority were observational studies. Most studies identified a correlation between larger nasal cross-sectional area or lower nasal resistance and higher CPAP compliance or lower CPAP pressures; however, nasal symptoms at baseline did not appear to affect CPAP use. The effect of CPAP on the nose remains uncertain: while most studies suggested increased mucosal inflammation with CPAP, those investigating symptoms presented contradictory results, with some reporting an increase and others an improvement in nasal symptoms. Evidence is clearer for nasal surgery leading to an increase in CPAP compliance and a decrease in CPAP pressures, whereas there is little evidence available for the use of topical nasal steroids.
conclusionThere appears to be a link between nasal volumes or nasal resistance and CPAP compliance, an increase in nasal inflammation caused by CPAP and a beneficial effect of nasal surgery on CPAP usage, but no significant effect of CPAP on nasal patency or effect of topical steroids on CPAP compliance. Results are more mitigated with regard to the effect of nasal symptoms on CPAP use and vice versa, and further research in this area would help identify patients who may benefit from additional support or treatment alongside CPAP.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.