ReviewEuropean radiology experimental2021
Virtual non-calcium dual-energy CT: clinical applications.
Review in European radiology experimental, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it, 60 citations in OpenAlex.
- Diagnostic accuracy of dual-energy CT for bone marrow edema in patients with acute knee injury: a systematic review and meta-analysis.Journal of orthopaedic surgery and research · 2023Pooled it
- Challenging bone biopsies: what radiologists needs to know.Skeletal radiology · 2026Review
- Dual-energy CT virtual non-calcium imaging for differentiating pathologic from non-pathologic femoral fractures: a study of inexperienced non-radiologist readers.Skeletal radiology · 2026Article
- Feasibility of multi-energy CT and fat fraction MRI for characterizing active bone marrow response to pelvic external beam radiation therapy.Journal of applied clinical medical physics · 2026Article
- Understanding Photon-Counting CT: Physics, Detector Technology, and Image Reconstructions.Sensors (Basel, Switzerland) · 2026Review
- The Role of SIRT1 in Mediating Bone Marrow Edema and Its Interface With Bone Remodeling.Immunity, inflammation and disease · 2026Review
- Diagnostic accuracy of dual-energy CT virtual non-calcium imaging for detecting spinal metastases: a retrospective comparison with conventional CT.Skeletal radiology · 2026Article
- Review
- Voxel-wise deep learning segmentation of hydroxyapatite and iodine in spectral photon-counting CT: A quantitative phantom study.PloS one · 2026Article
- The role of dual-energy CT in head and neck emergency.Emergency radiology · 2025Review
- Italian radiologists and dual-energy CT: a state of the art from a shared document by the computed tomography subspecialty section of the Italian society of radiology.La Radiologia medica · 2025Article
- Dual-Energy Computed Tomography for the Detection of Bone Edema-Like Lesions in the Equine Foot: Standing Horses and Cadaveric Specimens.Veterinary sciences · 2025Article
- Diagnostic accuracy of virtual non-calcium dual-energy computed tomography in the detection of acute occult ankle and calcaneus fractures.Quantitative imaging in medicine and surgery · 2025Article
- Breast cancer assessment under neoadjuvant systemic therapy using thoracic photon-counting detector computed tomography in prone position: a pilot study.European radiology experimental · 2025Article
- Improved visualization of electron-density dual-energy computed tomography for lumbar disc disease over the standard gray-scale type and virtual noncalcium imaging.Quantitative imaging in medicine and surgery · 2025Article
- Toward the Application of Dual-Energy Computed Tomography with Virtual Non-Hydroxyapatite Color-Coded Maps to Identify Traumatic Fractures in Daily Emergency Settings.Journal of imaging · 2024Article
- Carotid artery calcium score: Definition, classification, application, and limits.The neuroradiology journal · 2024Article
- Assessment of thoracic disc degeneration using dual-energy CT-based collagen maps.European radiology experimental · 2024Article
- Dual-energy CT in musculoskeletal imaging: technical considerations and clinical applications.La Radiologia medica · 2024Review
- What to Expect (and What Not) from Dual-Energy CT Imaging Now and in the Future?Journal of imaging · 2024Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Dual-energy CT (DECT) has emerged into clinical routine as an imaging technique with unique postprocessing utilities that improve the evaluation of different body areas. The virtual non-calcium (VNCa) reconstruction algorithm has shown beneficial effects on the depiction of bone marrow pathologies such as bone marrow edema. Its main advantage is the ability to substantially increase the image contrast of structures that are usually covered with calcium mineral, such as calcified vessels or bone marrow, and to depict a large number of traumatic, inflammatory, infiltrative, and degenerative disorders affecting either the spine or the appendicular skeleton. Therefore, VNCa imaging represents another step forward for DECT to image conditions and disorders that usually require the use of more expensive and time-consuming techniques such as magnetic resonance imaging, positron emission tomography/CT, or bone scintigraphy. The aim of this review article is to explain the technical background of VNCa imaging, showcase its applicability in the different body regions, and provide an updated outlook on the clinical impact of this technique, which goes beyond the sole improvement in image quality.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.