Evidence map›Paper›PMID 34476505›Full record

ArticleMolecular medicine reports2021

Overexpression of EphB4 promotes neurogenesis, but inhibits neuroinflammation in mice with acute ischemic stroke.

Jin Wang, Zun Zhang, Shaojing Fu, Xiaojie Li, Xinhui Li, Shaobin Wang, Lihe Yuan

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jin WangDepartment of Neurology, Inner Mongolia Baogang Hospital, Baotou, Inner Mongolia 014010, P.R. China.
Zun ZhangDepartment of Orthopedics, Inner Mongolia Baogang Hospital, Baotou, Inner Mongolia 014010, P.R. China.
Shaojing FuDepartment of Neurology, Inner Mongolia Baogang Hospital, Baotou, Inner Mongolia 014010, P.R. China.
Xiaojie LiDepartment of Neurology, Inner Mongolia Baogang Hospital, Baotou, Inner Mongolia 014010, P.R. China.
Xinhui LiDepartment of Neurology, First Affiliated Hospital of Baotou Medical College, Baotou, Inner Mongolia 014016, P.R. China.
Shaobin WangDepartment of Neurology, Inner Mongolia Baogang Hospital, Baotou, Inner Mongolia 014010, P.R. China.
Lihe YuanDepartment of Neurology, Inner Mongolia Baogang Hospital, Baotou, Inner Mongolia 014010, P.R. China.
Baogang Group (China) · CNBaotou Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ischemic stroke is one of the most common diseases that has a high rate of mortality, and has become a burden to the healthcare system. Previous research has shown that EPH receptor B4 (EphB4) promotes neural stem cell proliferation and differentiation

Indexed as

AnimalsCell DifferentiationCell ProliferationCyclin D1Disease Models, AnimalHumansInfarction, Middle Cerebral ArteryIschemic StrokeMaleMiceNeurogenesisNeuroinflammatory DiseasesNeuronsProto-Oncogene Proteins c-ablReceptor, EphB4Signal TransductionCcnd1 protein, mouseCyclin D1Ephb4 protein, mouseProto-Oncogene Proteins c-ablReceptor, EphB4ABL proto‑oncogene 1EPH receptor B4neurogenesisnon‑receptor tyrosine kinase/Cyclin D1 signalingstroke

Identifiers

PMID34476505
PMCPMC8436223
OpenAlexW3198016464

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.