Evidence map›Paper›PMID 34476501›Full record

ArticleMolecular medicine reports2021

Atrial natriuretic peptide protects vertebral endplate chondrocytes against H

Feiping He, Jingying Gai, Jun Wang, Lei Tang, Yifeng Liu, Qingchun Feng

Open access · hybridAbstract read
In one paragraph

Article in Molecular medicine reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.5field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. A Sulfated Polysaccharide fromMarine drugs · 2025
    Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Feiping HeDepartment of Spinal Surgery, The Second People's Hospital of Hunan Province, Brain Hospital of Hunan Province, Changsha, Hunan 410007, P.R. China.
Jingying GaiDepartment of Spinal Surgery, The Second People's Hospital of Hunan Province, Brain Hospital of Hunan Province, Changsha, Hunan 410007, P.R. China.
Jun WangDepartment of Spinal Surgery, The Second People's Hospital of Hunan Province, Brain Hospital of Hunan Province, Changsha, Hunan 410007, P.R. China.
Lei TangDepartment of Spinal Surgery, The Second People's Hospital of Hunan Province, Brain Hospital of Hunan Province, Changsha, Hunan 410007, P.R. China.
Yifeng LiuDepartment of Spinal Surgery, The Second People's Hospital of Hunan Province, Brain Hospital of Hunan Province, Changsha, Hunan 410007, P.R. China.
Qingchun FengDepartment of Cardiovascular Medicine, The Second People's Hospital of Hunan Province, Brain Hospital of Hunan Province, Changsha, Hunan 410007, P.R. China.
Second People Hospital of Hunan · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The present study aimed to investigate the effect of atrial natriuretic peptide (ANP) on cell apoptosis and oxidative stress in H

Indexed as

AnimalsApoptosisAtrial Natriuretic FactorCell Line, TumorChondrocytesHeme Oxygenase-1Hydrogen PeroxideIntervertebral DiscMembrane ProteinsMiceNF-E2-Related Factor 2Oxidative StressQuassinsSignal TransductionVertebral BodyAtrial Natriuretic FactorbrusatolHeme Oxygenase-1Hmox1 protein, mouseHydrogen PeroxideMembrane ProteinsNfe2l2 protein, mouseNF-E2-Related Factor 2QuassinsANPcell apoptosisEPCsNrf2/HO‑1 signaling pathwayoxidative stress

Identifiers

PMID34476501
PMCPMC8436219
OpenAlexW3197408334

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.