Evidence map›Paper›PMID 34476291›Full record

ArticleTransplantation direct2021

The Challenging Management of an Intracardiac Thrombus in a Liver Transplant Patient at the Reperfusion Phase: A Case Report and Brief Literature Review.

Luigi Vetrugno, Vittorio Cherchi, Dario Lorenzin, Francesco De Lorenzo, Marco Ventin, Victor Zanini, Giovanni Terrosu, Andrea Risaliti, Umberto Baccarani, Tiziana Bove

Abstract read
In one paragraph

Article in Transplantation direct, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Luigi VetrugnoDepartment of Anesthesia and Intensive Care, University-Hospital of Udine, Udine, Italy.
Vittorio CherchiGeneral Surgery Clinic and Liver Transplant Center, University-Hospital of Udine, Udine, Italy.
Dario LorenzinGeneral Surgery Clinic and Liver Transplant Center, University-Hospital of Udine, Udine, Italy.
Francesco De LorenzoDepartment of Anesthesia and Intensive Care, University-Hospital of Udine, Udine, Italy.
Marco VentinDepartment of Medicine, University of Udine, Italy, Udine, Italy.
Victor ZaniniDepartment of Anesthesia and Intensive Care, University-Hospital of Udine, Udine, Italy.
Giovanni TerrosuDepartment of Medicine, University of Udine, Italy, Udine, Italy.
Andrea RisalitiDepartment of Medicine, University of Udine, Italy, Udine, Italy.
Umberto BaccaraniDepartment of Medicine, University of Udine, Italy, Udine, Italy.
Tiziana BoveDepartment of Anesthesia and Intensive Care, University-Hospital of Udine, Udine, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The exact origin of intracardiac thrombi formation during orthotopic liver transplant remains unknown. The altered balance between hypercoagulability, hypocoagulation, and endothelial dysfunction associated with end-stage liver disease is thought to play a pivotal role. Venous stasis, vascular clamping, and reperfusion could also contribute to clot formation. The incidence of intracardiac thrombi formation stands at 4.2%, associated with a mortality rate of 45.5%, and to date, no consensus exists regarding the best way to treat this complication. Intraoperative transesophageal echocardiography is the only effective method for diagnosing intracardiac thrombi formation early, while point-of-care coagulation testing could guide the coagulation management potentially improving patient outcomes.

Identifiers

PMID34476291
PMCPMC8405129

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.