Evidence map›Paper›PMID 34476274›Full record

ArticleACG case reports journal2021

Multiorgan Dysfunction Related to Kratom Ingestion.

Muhammad Zarrar Khan, Mohannad Abou Saleh, Motasem Alkhayyat, Daniel E Roberts, Christina C Lindenmeyer

Abstract readCase Reports
In one paragraph

Article in ACG case reports journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Clinical Implications of Kratom (Current addiction reports · 2023
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Muhammad Zarrar KhanDepartment of Internal Medicine, Cleveland Clinic, Cleveland, OH.
Mohannad Abou SalehDepartment of Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic, Cleveland, OH.
Motasem AlkhayyatDepartment of Internal Medicine, Cleveland Clinic, Cleveland, OH.
Daniel E RobertsDepartment of Pathology, Cleveland Clinic, Cleveland, OH.
Christina C LindenmeyerDepartment of Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic, Cleveland, OH.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Consumption of herbal supplements has been linked to multiorgan toxicities. Kratom is an herbal extract that has gained popularity for its analgesic and psychotropic properties. Several cases of kratom-induced liver injury have been reported, but data on multiorgan involvement remain scarce. We present the case of a 37-year-old woman who developed a mixed hepatocellular and cholestatic pattern of acute liver injury, acute kidney injury, and pancolitis after prolonged use of kratom-containing herbal supplements.

Identifiers

PMID34476274
PMCPMC8389947

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.