ArticleERJ open research2021
Psychological stress and health-related quality of life among tuberculosis patients: a prospective cohort study.
Article in ERJ open research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07517471 (Start4All - Start Taking Action for TB Diagnosis SCREEN-TB), which is not on this map. Cited by 20 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Start4All - Start Taking Action for TB Diagnosis SCREEN-TB
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Association of smoking with depression among tuberculosis patients: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- Article
- Suicide risk in people with tuberculosis in Republic of Korea: a nationwide cohort, 2012-2021.Infectious diseases of poverty · 2026Article
- Thermal comfort in relation to housing and tuberculosis status among individuals aged ≥15 years in Padang, West Sumatra Province, Indonesia.Frontiers in public health · 2026Article
- Prevalence and associated factors of depression among persons with Tuberculosis in Ghana: A cross-sectional study.SAGE open medicine · 2026Article
- Identifying the attributes of adherence to tuberculosis treatment in Indonesia: A Delphi study.Narra J · 2025Article
- Article
- Factors influencing treatment success in drug-susceptible tuberculosis patients in Ghana: A prospective cohort study.PLOS global public health · 2025Article
- Stigma, depression, and quality of life among people with pulmonary tuberculosis diagnosed through active and passive case finding in Nepal: a prospective cohort study.BMC global and public health · 2024Article
- Person-centered and youth-oriented interventions to improve TB Care for adolescents and young adults.PLOS global public health · 2024Article
- Self-efficacy and self-management mediate the association of health literacy and quality of life among patients with TB in Tibet, China: a cross-sectional study.International health · 2023Article
- Depression, Anxiety, and Cigarette Smoking Among Patients with Tuberculosis.Clinical nursing research · 2023Article
- Observational
- A randomized controlled trial to evaluate the impact of pharmacist-led clinical interventions on the health-related quality of life among TB patients.Frontiers in pharmacology · 2023Article
- Determinants of quality of life among people with HIV and tuberculosis in an underserved area in Indonesia: a cross-sectional study.The Pan African medical journal · 2023Article
- Health-related quality of life of persons living with tuberculosis: A cross-sectional study.Journal of clinical tuberculosis and other mycobacterial diseases · 2022Article
- Association between depression or anxiety symptoms and immune-inflammatory characteristics in in-patients with tuberculosis: A cross-sectional study.Frontiers in psychiatry · 2022Article
- Correlates of quality of life among persons living with tuberculosis: A cross-sectional study.PloS one · 2022Article
- A 360-Degree View: An Autobiographical Case Report.Cureus · 2021Article
- Determinants of health-related quality of life in drug-susceptible tuberculosis patients in Ghana: a prospective observational study.Therapeutic advances in infectious diseaseArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Economic, social and psychological distress is common in individuals affected by tuberculosis (TB). However, the magnitude of distress, psychological interventions and their effect on the treatment outcomes are often under-evaluated. We examined the level of psychological stress and health-related quality of life (HRQoL) of such patients and the effect of antituberculosis therapy on them. Our prospective cohort study included newly diagnosed adult pulmonary and extrapulmonary TB patients. Assessment of psychological stress was done using the seven-item Generalised Anxiety Disorder questionnaire for anxiety and the nine-item Patient Health Questionnaire for depression. HRQoL was assessed by using the WHOQOL-BREF questionnaire. Of the 86 patients studied, 21 (24.4%) had anxiety symptoms at the baseline, which reduced to 5.8% and 1.2% at 2 months and treatment completion, respectively (p<0.001). Among the subjects, 18 (20.9%) patients had depression, which reduced to 7% and 2.3% at 2 months and treatment completion, respectively (p<0.001). All the mean domain scores of HRQoL were poor at the baseline, which showed improvement at treatment completion (p<0.001). Anxiety and depression were common among TB patients, and there was significant progressive reduction during and after treatment. TB had remarkable negative impacts on HRQoL, with the physical domain being the most affected, and all the domain scores showed significant improvement at treatment completion. Routine screening for depression and anxiety and timely referral to a psychiatrist are required in TB patients to improve the outcome of the disease and quality of life.
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Registered trials
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