ArticleQuantitative imaging in medicine and surgery2021
Risk factors for the progression of unruptured intracranial aneurysms in patients followed by CT/MR angiography.
Article in Quantitative imaging in medicine and surgery, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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11 citing papers in PubMed, 13 citations in OpenAlex.
- Article
- Impact of anatomical variations of the circle of Willis on the blood flow within unruptured intracranial aneurysm.Quantitative imaging in medicine and surgery · 2025Article
- Correlation of plasma plectin levels with small intracranial aneurysms instability and prognosis.Neurosurgical review · 2025Article
- The effect of clinical, bifurcation, and aneurysm morphological characteristics on the risk of rupture in internal carotid artery bifurcation aneurysms.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2025Observational
- Assessment of the stability of intracranial aneurysms using a deep learning model based on computed tomography angiography.La Radiologia medica · 2025Article
- Compare deep learning model and conventional logistic regression model for the identification of unstable saccular intracranial aneurysms in computed tomography angiography.Quantitative imaging in medicine and surgery · 2024Article
- Intracranial aneurysm rupture risk in northern China: a retrospective case-control study.Quantitative imaging in medicine and surgery · 2024Article
- Clinical Scales in Aneurysm Rupture Prediction.Stroke (Hoboken, N.J.) · 2024Review
- Hounsfield unit as a predictor of symptomatic vasospasm and hydrocephalus in good-grade subarachnoid hemorrhage treated with endovascular coiling.Quantitative imaging in medicine and surgery · 2023Article
- Low-profile visualized intraluminal support-within-Enterprise overlapping-stent technique versus flow diversion in the treatment of intracranial vertebrobasilar trunk dissecting aneurysms.Quantitative imaging in medicine and surgery · 2023Article
- Increased Levels of Serum IL-15 and TNF-β Indicate the Progression of Human Intracranial Aneurysm.Frontiers in aging neuroscience · 2022Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe progression of an unruptured intracranial aneurysm (UIA) is associated with a higher rupture risk. The aim of this study was to identify the risk factors for the progression of UIAs among Chinese adults and compare them with the ELAPSS (Earlier subarachnoid hemorrhage, IA Location, Age, Population, IA Size and Shape) score.
methodsFour hundred thirty-eight consecutive patients with 491 UIAs were followed and reviewed retrospectively from August 2011 to November 2019. Follow-up images of the UIAs were used to determine changes in IA size and shape. Patients and IAs were divided into non-progression and progression groups. In addition to the clinical characteristics of the patients, the features of the IAs (e.g., size and shape) were evaluated by computed tomography angiography (CTA) or magnetic resonance angiography (MRA). Independent risk factors for UIA progression were studied using multiple Cox proportional hazards regression analysis. In addition, the diagnostic value of the ELAPSS score for the prediction of UIA progression was calculated.
resultsSeventy-two IAs in 68 patients progressed during a mean follow-up time of 24.2±19.68 months. IAs located at the bifurcation [odds ratio (OR) 2.600], with an irregular shape (OR 2.981) or having a high aspect ratio (AR, OR 2.430) were correlated with progression. Based on these three factors, the threshold value of our predictive score was 0.5, and the area under the curve (AUC), sensitivity and specificity were 0.756, 93.1% and 40.6%, respectively, while the AUC, sensitivity and specificity of the ELAPSS score were 0.711, 55.6%, and 75.2%, respectively.
conclusionsIAs located at the bifurcation, with an irregular shape and with an elevated AR are risk factors for UIA progression in the Chinese population. Our predictive score is of great value in predicting the risk of UIA progression.
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