Evidence map›Paper›PMID 34476093›Full record

ArticleClinical kidney journal2021

Choice of dialysis modality among patients initiating dialysis: results of the Peridialysis study.

James Heaf, Maija Heiro, Aivars Petersons, Baiba Vernere, Johan V Povlsen, Anette Bagger Sørensen, Naomi Clyne, Inge Bumblyte, Alanta Zilinskiene, Else Randers and 8 more

Open access · goldAbstract read
In one paragraph

Article in Clinical kidney journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 24 citations in OpenAlex.

  1. Peritoneal Dialysis Initiation Patterns by Health Service Area during an Era of Expansion.Journal of the American Society of Nephrology : JASN · 2026
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  12. Patient perspectives on peritoneal dialysis (PD) and the PD catheter: Strategies and Solutions.Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis · 2023
    Article
  13. Adding creatinine to routine pregnancy tests: a decision tree for calculating the cost of identifying patients with CKD in pregnancy.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Article
  14. Transitions between dialysis modalities.Journal of nephrology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 14 institutions in 7 countries.

James HeafDepartment of Medicine, Zealand University Hospital, Roskilde, Denmark.ORCID https://orcid.org/0000-0003-3715-3388
Maija HeiroDepartment of Medicine, Turku University Hospital, Turku, Finland.
Aivars PetersonsLatvia Nephrology Department, P. Stradins University Hospital, Riga, Latvia.
Baiba VernereLatvia Nephrology Department, P. Stradins University Hospital, Riga, Latvia.
Johan V PovlsenDepartment of Nephrology, Aarhus University Hospital, Aarhus, Denmark.
Anette Bagger SørensenDepartment of Nephrology, Aarhus University Hospital, Aarhus, Denmark.
Naomi ClyneDepartment of Nephrology, Clinical Sciences Lund, Lund University, Skåne University Hospital, Malmö, Sweden.ORCID https://orcid.org/0000-0001-5284-4406
Inge BumblyteNephrological Clinic, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Alanta ZilinskieneNephrological Clinic, Lithuanian University of Health Sciences, Kaunas, Lithuania.
Else RandersDepartment of Medicine, Viborg Regional Hospital, Viborg, Denmark.
Niels LøkkegaardDepartment of Medicine, Holbaek Hospital, Holbaek, Denmark.
Mai Ots-RosenbergDepartment of Nephrology, University Hospital of Tartu, Tartu, Estonia.
Stig KjellevoldDepartment of Medicine, Vestfold Hospital, Tønsberg, Norway.
Jan Dominik KampmannDepartment of Nephrology, Hospital of Southern Jutland, Soenderborg, Denmark.
Björn RoglandDepartment of Medicine, Kristianstad Hospital, Kristianstad, Sweden.
Inger LagreidDepartment of Medicine, St Olav University Hospital, Trondheim, Norway.
Olof HeimburgerDepartment of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Bengt LindholmDepartment of Clinical Science, Intervention and Technology, Karolinska Institutet, Stockholm, Sweden.
Aarhus University Hospital · DKKarolinska Institutet · SELithuanian University of Health Sciences · LTPauls Stradiņš Clinical University Hospital · LVHolbæk Sygehus · DKKristianstad University · SELund University · SERegionshospitalet Viborg · DKSt Olav's University Hospital · NOSygehus Sønderjylland · DKSykehuset i Vestfold · NOTartu University Hospital · EETurku University Hospital · FIUniversity of Copenhagen · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn patients with end-stage kidney disease (ESKD), home dialysis offers socio-economic and health benefits compared with in-centre dialysis but is generally underutilized. We hypothesized that the pre-dialysis course and institutional factors affect the choice of dialysis modality after dialysis initiation (DI).

methodsThe Peridialysis study is a multinational, multicentre prospective observational study assessing the causes and timing of DI and consequences of suboptimal DI. Clinical and biochemical data, details of the pre-dialytic course, reasons for DI and causes of the choice of dialysis modality were registered.

resultsAmong 1587 included patients, 516 (32.5%) were judged unsuitable for home dialysis due to contraindications [384 ( 24.2%)] or no assessment [106 (6.7%); mainly due to late referral and/or suboptimal DI] or death [26 (1.6%)]. Older age, comorbidity, late referral, suboptimal DI, acute illness and rapid loss of renal function associated with unsuitability. Of the remaining 1071 patients, 700 (65.4%) chose peritoneal dialysis (61.7%) or home haemodialysis (HD; 3.6%), while 371 (34.6%) chose in-centre HD. Somatic differences between patients choosing home dialysis and in-centre dialysis were minor; factors linked to the choice of in-centre dialysis were late referral, suboptimal DI, acute illness and absence of a 'home dialysis first' institutional policy.

conclusionsGiven a personal choice with shared decision making, 65.4% of ESKD patients choose home dialysis. Our data indicate that the incidence of home dialysis potentially could be further increased to reduce the incidence of late referral and unplanned DI and, in acutely ill patients, by implementing an educational programme after improvement of their clinical condition.

Indexed as

glomerular filtration ratehaemodialysisperitoneal dialysispre-dialysisuraemia

Identifiers

PMID34476093
PMCPMC8406075
OpenAlexW3116559125

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.