Evidence map›Paper›PMID 34476030›Full record

ArticleJournal of children's orthopaedics2021

Does the vascular development of the femoral head correlate with the incidence of avascular necrosis of the proximal femoral epiphysis in children with developmental dysplasia of the hip treated by closed reduction?

JianPing Wu, Zhe Yuan, JingChun Li, MingWei Zhu, Federico Canavese, Xun Fuxing, YiQiang Li, HongWen Xu

Abstract read
In one paragraph

Article in Journal of children's orthopaedics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

JianPing WuDepartment of Pediatric Orthopaedics, GuangZhou Women and Children's Medical Center, GuangZhou, China.
Zhe YuanDepartment of Pediatric Orthopaedics, GuangZhou Women and Children's Medical Center, GuangZhou, China.
JingChun LiDepartment of Pediatric Orthopaedics, GuangZhou Women and Children's Medical Center, GuangZhou, China.
MingWei ZhuDepartment of Pediatric Orthopaedics, GuangZhou Women and Children's Medical Center, GuangZhou, China.
Federico CanaveseDepartment of Pediatric Orthopaedics, GuangZhou Women and Children's Medical Center, GuangZhou, China.ORCID https://orcid.org/0000-0002-6114-5372
Xun FuxingDepartment of Pediatric Orthopaedics, GuangZhou Women and Children's Medical Center, GuangZhou, China.
YiQiang LiDepartment of Pediatric Orthopaedics, GuangZhou Women and Children's Medical Center, GuangZhou, China.
HongWen XuDepartment of Pediatric Orthopaedics, GuangZhou Women and Children's Medical Center, GuangZhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe purpose of this study was to identify the correlation between the vascular development of the femoral head and avascular necrosis (AVN) in patients with developmental dysplasia of the hip (DDH) treated by closed reduction (CR).

methodsWe retrospectively reviewed 78 patients with DDH treated by CR (83 hips). The vascular maturity, number of vessels and perfusion changes of the femoral head were assessed on perfusion MRI (pMRI) before and after CR.

resultsThe number of vessels (mean 4.2 sd 1.4) of the femoral head and the ratio (36.1%) of mature vessels (type III) on the dislocated side were significantly less than those at contralateral side (mean 6.0 sd 1.2; 82.2%) (p < 0.001). Of the included 83 hips, 39 hips (61.5%) showed decreased perfusion of the femoral head, including partial decreased (Class B, 47.0%) and global decreased (Class C, 14.5%), at the dislocated side, which was significantly more than those at contralateral side (0.0%) (p < 0.001). In total, 32 out of 83 hips (38.5%) developed AVN. The rate of AVN with Class A (18.8%) which perfusion of the femoral head was normal (unchanged or enhanced) was significantly less than those with Class C (66.7%) (p = 0.006).

conclusionThe vascular development and perfusion changes of the femoral head on the dislocated side are significantly worse than those at contralateral side. Immature vascularity of the femoral head before CR and poor perfusion of the femoral head after CR may be risk factors for AVN in patients with DDH. LEVEL OF EVIDENCE: III.

Indexed as

avascular necrosisclosed reductiondevelopmental dysplasia of the hipfemoral headvascular development

Identifiers

PMID34476030
PMCPMC8381394

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.