ArticleJournal of children's orthopaedics2021
Primary malignant bone tumours of spine and pelvis in children.
Article in Journal of children's orthopaedics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 9 citations in OpenAlex.
- Clinicopathological features and survival disparities between axial and appendicular skeletal Angiosarcoma: A SEER-based analysis using competing risk models.Journal of bone oncology · 2026Article
- Pediatric vertebral tumors: radiologic features and differential diagnoses.Pediatric radiology · 2026Review
- MORTALITY PROFILE FROM PEDIATRIC BONE NEOPLASIA IN MINAS GERAIS (2015-2024).Acta ortopedica brasileira · 2026Article
- Tumors and infections of the growing spine.Journal of children's orthopaedics · 2023Review
- Article
- Pain and Analgesia in Children with Cancer after Hemipelvectomy: A Retrospective Analysis.Children (Basel, Switzerland) · 2022Article
- Construction, Validation, and Visualization of Two Web-Based Nomograms for Predicting Overall Survival and Cancer-Specific Survival in Elderly Patients with Primary Osseous Spinal Neoplasms.Journal of oncology · 2022Article
- Malignant bone tumours in children: What's up?Journal of children's orthopaedics · 2021Article
- Imaging of primary vertebral tumors and tumor-like lesions in skeletally immature patients: a pictorial review.Radiologia brasileiraReview
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeAxial malignant bone tumours are rare in children and adolescents, and their prognosis is still relatively poor due to non-specific symptoms, such as back or groin pain, which may result in late hospital presentation. Therefore, it is very important to raise awareness regarding this pathology.
methodsWe performed a narrative review, including scientific publications published in English. We searched Medline and Google Scholar databases for information on the incidence and prognosis of axial malignant bone tumours in children and adolescents (< 18 years). Outcomes of different surgical management strategies and reconstruction options were assessed.
resultsThe incidence of primary malignant bone tumours before the age of 18 years is approximately five per one million population; around 25% of these tumours are located in the axial skeleton. With a five-year survival rate of 50%, tumours in an axial location (chest cage, spine, pelvis) are associated with a poorer prognosis than tumours in more peripheral locations.
conclusionEarly diagnosis, a timely adequate multidisciplinary management, appropriate LEVEL OF EVIDENCE: V.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.