Evidence map›Paper›PMID 34475924›Full record

ArticlePakistan journal of medical sciences

Effectiveness of Chlorhexidine and Metronidazole Gels in the management of gingivitis. A clinical trial.

Maryam Panhwar, Shazia Parveen Rajpar, Eisha Abrar, Montaser Alqutub, Tariq Abduljabbar

Open access · goldAbstract read
In one paragraph

Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Maryam PanhwarMaryam Panhwar, Department of Community and Preventive Dentistry, Dow International Dental College, Karachi Pakistan.
Shazia Parveen RajparShazia Parveen Rajpar, Department of Community and Preventive Dentistry, Liaquat University of Medical Health Sciences Jamshoro.
Eisha AbrarEisha Abrar, MDS Trainee Department of Operative Dentistry, Dow International Dental College, Karachi Pakistan.
Montaser AlqutubMontaser Alqutub, Department of Periodontics and Community Dentistry, College of Dentistry, King Saud University, Riyadh, Saudi Arabia.
Tariq AbduljabbarTariq Abduljabbar Department of Prosthetic Dental Science, College of Dentistry, King Saud University; Research Chair for Biological Research in Dental Health , College of Dentistry, Riyadh 11545, Saudi Arabia.
Prosthetic Design + Research (United States) · USKing Saud University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe purpose of the present study was to compare the topical application of chlorohexidine (CHX) and Metronidazole (MTZ) gels, individually and in combination in patients with gingivitis for up to 12 weeks follow-up.

methodsThe clinical trial was conducted at Liaquat University of Medical Health Sciences (LUMHS) Jamshoro and Hyderabad, Institute of Dentistry from 1

resultsA significant improvement in gingival scores was noted in all groups from baseline. At 4 weeks CHX (1.25±0.21) MTZ (1.81±0.38) CHX+MTZ (1.29±0.34) compared to baseline CHX (2.77±0.24) MTZ (2.84±0.54) CHX+MTZ (2.74±0.31) demonstrated substantial improvement (p<0.001). However, gingival scores showed inclination at 12 weeks CHX (1.18±0.41) MTZ (1.21±0.48) CHX+MTZ (1.11±0.14) with no significant difference to week 4 (p>0.001).

conclusionLocal MTZ gel and MTZ+CHX gel showed effectiveness similar to CHX gel application adjunct to scaling and root planning in the treatment of gingivitis.

Indexed as

ChlorohexidineGingivitisMetronidazoleRandomized clinical trial

Identifiers

PMID34475924
PMCPMC8377906
OpenAlexW3173999030

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.