ArticlePakistan journal of medical sciences
Postnatal causes and severity of persistent pulmonary Hypertension of Newborn.
Article in Pakistan journal of medical sciences. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Oral sildenafil versus bosentan for treatment of persistent pulmonary hypertension of the newborn: a randomized controlled trial.BMC pediatrics · 2024Trial
- Clinical profile, survival outcomes, and predictors of mortality in neonates with persistent pulmonary hypertension: a follow-up study from Hawassa, Ethiopia.BMC pediatrics · 2026Article
- Prevalence and severity of persistent pulmonary hypertension of the newborns among asphyxiated neonates admitted in Enugu State University Teaching Hospital.BMJ paediatrics open · 2026Article
- Global, regional and national trends in the burden of persistent pulmonary hypertension of the newborn and essentials of its management from 1993 to 2023: a scoping review.Frontiers in pediatrics · 2025Review
- [Application of exchange transfusion in neonates with severe pertussis and hyperleukocytosis].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024Article
- Caesarean section and respiratory system disorders in newborns.European journal of obstetrics & gynecology and reproductive biology: X · 2024Review
- Novel scoring tool of hypoxemic respiratory failure and pulmonary hypertension for defining severity of persistent pulmonary hypertension of newborn.Journal of perinatology : official journal of the California Perinatal Association · 2023Article
- Management of neonatal pulmonary hypertension-a survey of neonatal intensive care units in India.BMC pediatrics · 2023Article
- Article
- Burden of cardiovascular dysfunction and outcome among term newborns having birth asphyxia.Pakistan journal of medical sciencesArticle
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4 authors.
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Abstract
BACKGROUND &
objectivePersistent pulmonary hypertension of the newborn (PPHN) is described as severe respiratory failure along with hypoxaemia. PPHN is known to be linked with high morbidity and mortality around the world. This study was planned to determine the postnatal causes and assess the severity of persistent pulmonary hypertension of newborn in babies presenting to the Children's Hospital, Multan.
methodsThis observational study was conducted at the Department of Paediatric Cardiology, The Children Hospital &Institute of Child Health, Multan, Pakistan from July to December 2019. A total of 122 confirmed cases of PPHN admitted having gestational age above 34 weeks were enrolled. Demographic data of the newborns was recorded along with maternal medical history, pregnancy status and postnatal causes of PPHN. Severity of PPHN was also recorded.
resultsOut of a total of 122 cases of PPHN, 81 (66.3%) were male. Majority, 78 (64.0%) had gestational age above 37 weeks. Mode of delivery as cesarean section was noted in 70 (57.4%). Meconium aspiration syndrome 52 (42.6%), birth asphyxia 48 (39.3%), respiratory distress syndrome 23 (18.8%) and sepsis 33 (27.0%) were found to be the commonest causes of PPHN. Severe PPHN was found to be the most frequent, noted among 63 (51.6%) while Moderate PPHN was observed in 40 (32.8%) and Mild PPHN in 19 (15.6%). Morality was noted among 26 (21.3%) of cases.
conclusionMeconium aspiration syndrome, birth asphyxia and respiratory distress syndrome were the commonest postnatal causes of PPHN. Severe PPHN was found to be the most frequent form of PPHN.
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