Evidence map›Paper›PMID 34475780›Full record

ArticleInternational journal of general medicine2021

Neutrophil Gelatinase-Associated Lipocalin Contributes to Increased Risk of Cardiovascular Death After Acute Coronary Syndrome.

Huogen Liu, Xin Wan, Yundi Shi, Fengming Huang, Hailin Shu, Rijin Huang, Ling Gu

Open access · goldAbstract read
In one paragraph

Article in International journal of general medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Huogen LiuDepartment of Critical Care Medicine, Mindong Hospital Affiliated to Fujian Medical University, Fu'an City, Fujian Province, 355000, People's Republic of China.ORCID 0000-0003-1554-3836
Xin WanDepartment of Critical Care Medicine, Mindong Hospital Affiliated to Fujian Medical University, Fu'an City, Fujian Province, 355000, People's Republic of China.
Yundi ShiDepartment of Critical Care Medicine, Mindong Hospital Affiliated to Fujian Medical University, Fu'an City, Fujian Province, 355000, People's Republic of China.
Fengming HuangDepartment of Critical Care Medicine, Mindong Hospital Affiliated to Fujian Medical University, Fu'an City, Fujian Province, 355000, People's Republic of China.
Hailin ShuDepartment of Critical Care Medicine, Mindong Hospital Affiliated to Fujian Medical University, Fu'an City, Fujian Province, 355000, People's Republic of China.
Rijin HuangDepartment of Critical Care Medicine, Mindong Hospital Affiliated to Fujian Medical University, Fu'an City, Fujian Province, 355000, People's Republic of China.
Ling GuDepartment of Critical Care Medicine, Mindong Hospital Affiliated to Fujian Medical University, Fu'an City, Fujian Province, 355000, People's Republic of China.
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNeutrophil gelatinase-associated lipocalin (NGAL) has been suggested to reflect early renal dysfunction. We investigated the predictive significance of serum NGAL in predicting cardiovascular (CV) death in an old-age population with coronary heart disease (CHD).

methodsIn total, 633 CHD patients with a stable clinical condition were enrolled. The measurements of serum NGAL and other laboratory indices were performed within 24 hours after admission. Adjusted analysis was used to assess relationships between serum NGAL and CV death during the 10-year follow-up period.

resultsMultivariate logistic regression analysis demonstrated that elevated NGAL levels were related to a higher prevalence of CV disease history [quartile 4, 2.41 (1.60-4.59),

conclusionSerum levels of NGAL were elevated in patients with CHD and may be a new parameter that could independently predict CV death in these patients, which may strengthen its potential application in clinical practice.

Indexed as

cardiovascular deathischemic heart diseaseneutrophil gelatinase-associated lipocalin

Identifiers

PMID34475780
PMCPMC8407785
OpenAlexW3195771821

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.