Evidence map›Paper›PMID 34475757›Full record

ArticleInternational journal of nanomedicine2021

Biodistribution of

Sandra Díez-Villares, Juan Pellico, Noemí Gómez-Lado, Santiago Grijalvo, Sandra Alijas, Ramon Eritja, Fernando Herranz, Pablo Aguiar, María de la Fuente

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Review
  7. Article
  8. Nanoscale Radiotheranostics for Cancer Treatment: From Bench to Bedside.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Sandra Díez-VillaresNano-Oncology and Translational Therapeutics group, Health Research Institute of Santiago de Compostela (IDIS), SERGAS, Santiago de Compostela, 15706, Spain.ORCID 0000-0002-3311-7710
Juan PellicoSchool of Biomedical Engineering & Imaging Sciences, King's College London, St. Thomas' Hospital, London, SE1 7EH, UK.ORCID 0000-0003-2787-8641
Noemí Gómez-LadoNuclear Medicine Department and Molecular Imaging Group, Health Research Institute of Santiago de Compostela (IDIS), SERGAS, Santiago de Compostela, 15706, Spain.ORCID 0000-0003-2362-3051
Santiago GrijalvoInstitute for Advanced Chemistry of Catalonia (IQAC), Consejo Superior de Investigaciones Científicas (CSIC), Barcelona, E-08034, Spain.ORCID 0000-0002-8405-4844
Sandra AlijasNano-Oncology and Translational Therapeutics group, Health Research Institute of Santiago de Compostela (IDIS), SERGAS, Santiago de Compostela, 15706, Spain.
Ramon EritjaInstitute for Advanced Chemistry of Catalonia (IQAC), Consejo Superior de Investigaciones Científicas (CSIC), Barcelona, E-08034, Spain.ORCID 0000-0001-5383-9334
Fernando HerranzBiomedical Research Networking Center on Respiratory Diseases (CIBERES), Madrid, 28029, Spain.ORCID 0000-0002-3743-0050
Pablo AguiarNuclear Medicine Department and Molecular Imaging Group, Health Research Institute of Santiago de Compostela (IDIS), SERGAS, Santiago de Compostela, 15706, Spain.ORCID 0000-0002-7322-2195
María de la FuenteNano-Oncology and Translational Therapeutics group, Health Research Institute of Santiago de Compostela (IDIS), SERGAS, Santiago de Compostela, 15706, Spain.ORCID 0000-0003-0322-1469

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeNon-invasive imaging methodologies, especially nuclear imaging techniques, have undergone an extraordinary development over the last years. Interest in the development of innovative tracers has prompted the emergence of new nanomaterials with a focus on nuclear imaging and therapeutical applications. Among others, organic nanoparticles are of the highest interest due to their translational potential related to their biocompatibility and biodegradability. Our group has developed a promising new type of biocompatible nanomaterials, sphingomyelin nanoemulsions (SNs). The aim of this study is to explore the potential of SNs for nuclear imaging applications.

methodsReady-to-label SNs were prepared by a one-step method using lipid derivative chelators and characterized in terms of their physicochemical properties. Stability was assessed under storage and after incubation with human serum. Chelator-functionalized SNs were radiolabeled with

resultsHere, we describe a simple and mild one-step method for fast and efficient radiolabeling of SNs with

conclusionThis work supports

Indexed as

Positron-Emission TomographySphingolipidsGallium RadioisotopesHumansRadiopharmaceuticalsTissue DistributionTomography, Emission-Computed, Single-PhotonGallium RadioisotopesRadiopharmaceuticalsSphingolipidsbiodistributiongallium-68/67nanotheranosticsnuclear imagingsphingomyelin nanoemulsions

Identifiers

PMID34475757
PMCPMC8405882

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.