Evidence map›Paper›PMID 34475753›Full record

ArticlePatient preference and adherence2021

Translation, Cultural Adaptation and Validation of General Medication Adherence Scale (GMAS) into the Nepalese Language.

Rajeev Shrestha, Binaya Sapkota, Asmita Priyadarshini Khatiwada, Sunil Shrestha, Saval Khanal, Bhuvan Kc, Vibhu Paudyal

Registry-linked trialAbstract read
In one paragraph

Article in Patient preference and adherence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05707481 (Impact of Clinical Pharmacist Led Intervention on Management of Diabetic Hypertensive Patients.), which is not on this map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05707481 nacompletednot on this mapstarted 2023, after this paper: background citation

Impact of Clinical Pharmacist Led Intervention on Management of Diabetic Hypertensive Patients.

TypeinterventionalSponsorChettinad Academy of Research and Education (Deemed to be University)Ran2023 to 2024Enrolled92ConditionsType 2 Diabetes, HypertensionArmsClinical Pharmacist-Led Educational Intervention
3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rajeev Shrestha *Department of Pharmacy, District Hospital Lamjung, Besisahar, Province Gandaki, Nepal.ORCID 0000-0003-1822-3969
Binaya Sapkota *Department of Pharmaceutical Sciences, Nobel College, Affiliated to Pokhara University, Kathmandu, Province Bagmati, Nepal.ORCID 0000-0002-4125-9866
Asmita Priyadarshini KhatiwadaDepartment of Pharmaceutical and Health Service Research, Nepal Health Research and Innovation Foundation, Lalitpur, Province Bagmati, Nepal.ORCID 0000-0001-6532-2439
Sunil Shrestha *School of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, 47500, Malaysia.ORCID 0000-0002-9174-7120
Saval KhanalDivision of Health Sciences, Warwick Medical School, University of Warwick, Coventry, UK.ORCID 0000-0001-5201-0612
Bhuvan KcSchool of Pharmacy, Monash University Malaysia, Bandar Sunway, Selangor, 47500, Malaysia.ORCID 0000-0002-9135-962X
Vibhu PaudyalInstitute of Clinical Sciences, College of Medical and Dental Sciences, University of Birmingham, Birmingham, UK.ORCID 0000-0002-4173-6490

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe General Medication Adherence Scale (GMAS) evaluates intentional and unintentional behaviour of patients, disease and medication burden and cost-related burden associated with non-adherence. GMAS was developed and validated among Urdu-speaking patients with chronic diseases. However, validated tool in Nepalese language to measure medication adherence among chronic illness patients currently does not exist.

aimTo translate, culturally adapt, and validate the English version of GMAS into the Nepalese language to measure medication adherence among chronic illness patients.

methodsThe study was conducted among patients with chronic diseases in both hospital and community pharmacies of Nepal. The International Society for Pharmacoeconomics and Outcomes Research (ISPOR) Good Practice Guideline for linguistic translation and cultural adaptation was used to translate and culturally adapt the English version of GMAS into the Nepalese version. The translated version was validated amongst patients with chronic diseases in Nepal. Exploratory factor analysis was carried out using principal component analysis with varimax rotation. Test-retest reliability and internal consistency were analysed.

resultsA total of 220 (53.6% females, and 51.4% of 51 to 70 aged patients) patients with chronic diseases participated in the study. The majority of patients took two medications (27.3%) from six months to five and half years (68.2%). Kaiser Meyer Olkin was found to be 0.83. A principal axis factor analysis was conducted on the 3 items of GMAS without and with orthogonal rotation (varimax). The scree plot showed an inflexion on the third item that meant three components were present. The overall Cronbach's alpha value of the full-phase study was 0.82.

conclusionThe General Medication Adherence Scale was successfully translated into the Nepalese language, culturally adapted, and validated amongst chronic diseases patients of Nepal. Therefore, the GMAS-Nepalese version can be used to evaluate medication adherence among Nepalese-speaking patients with chronic disease.

Indexed as

adherencechronic diseasegeneral medication adherence scaleGMASNepalpsychometric validation

Identifiers

PMID34475753
PMCPMC8407778

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.