ArticleAnnals of gastroenterology
Short versus standard peroral endoscopic myotomy for esophageal achalasia: a systematic review and meta-analysis.
Article in Annals of gastroenterology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 2 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Short versus standard esophageal myotomy during peroral endoscopic myotomy for achalasia: A systematic review and meta-analysis of randomized controlled trials.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026Pooled it
- Impact of myotomy length on per-oral endoscopic myotomy (POEM) outcomes for achalasia: a meta-analysis of randomized trials.Surgical endoscopy · 2025Pooled it
- Objective GERD following POEM significantly increased by length of myotomy.Surgical endoscopy · 2026Article
- Short versus long myotomy during peroral endoscopic myotomy for achalasia: a systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2026Article
- The per-oral endoscopic myotomy (POEM) era in Saudi Arabia: Bridging tertiary-center experience with clinical care pathways.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2026Article
- Mastering the third space: Innovations in intramural endoscopic surgery for gastrointestinal disorders.World journal of gastrointestinal endoscopy · 2025Review
- Evolving Indications of Esophageal Peroral Endoscopic Myotomy (E-POEM): A Review of Expanding Applications in Esophageal Pathologies.Current gastroenterology reports · 2025Review
- Does Short Myotomy Really Not Reduce the Risk of Reflux Esophagitis and Pathologic Acid Exposure After Peroral Endoscopic Myotomy?Digestive diseases and sciences · 2025Article
- Reflux after peroral endoscopic myotomy: The dilemma and the options.World journal of gastroenterology · 2025Article
- Modern Achalasia: Diagnosis, Classification, and Treatment.Journal of neurogastroenterology and motility · 2023Review
- Third-space endoscopy: the final frontier.Gastroenterology report · 2023Review
- Publication trends of peroral endoscopic myotomy during 2010-2022: a bibliometric analysis.Annals of translational medicine · 2022Article
- Peroral Endoscopy Myotomy (POEM) for Esophageal Motility Disorders.Current gastroenterology reports · 2022Review
- Changes in Distensibility Index During an Incremental POEM Myotomy.Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract · 2022Article
- Modified Peroral Endoscopic Myotomy Technique for Type II Achalasia: A Multicenter Retrospective Study.Gastroenterology research and practice · 2022Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPeroral endoscopic myotomy (POEM) is increasingly used to treat esophageal achalasia, but is associated with a high rate of gastroesophageal reflux disease (GERD). The aim of our meta-analysis was to compare short and standard POEM in terms of clinical success and postoperative GERD.
methodsWe conducted a systematic review and meta-analysis of studies that compared POEM using short myotomy with standard myotomy. The primary outcome was clinical success. Secondary outcomes were postoperative GERD, perioperative complications, operation time, and length of hospital stay. A random-effects model was used to calculate the risk ratios (RR), mean differences (MD), and confidence intervals (CI). A P-value <0.05 was considered statistically significant.
resultsWe included 5 studies involving 474 esophageal achalasia patients. Short and standard myotomies were similar in terms of clinical success (RR 1.02, 95%CI 0.97-1.09), perioperative complications (RR 0.68, 95%CI 0.26-1.75), and length of hospital stay (MD 0.25 days, 95%CI -0.14-0.63). Operation time was shorter for short myotomy (MD -15.01 mins, 95%CI -20.34 - -9.67). Although reflux symptoms were similar (RR 0.94, 95%CI 0.51-1.74), short myotomy had a lower risk of reflux esophagitis on endoscopy (RR 0.61, 95%CI 0.39-0.98), and pathologic acid exposure on pH monitoring (RR 0.58, 95%CI 0.36-0.94).
conclusionsPOEM using a shorter myotomy is comparable with standard myotomy in terms of efficacy and safety in the short-term setting. A short myotomy requires a shorter operation time and might reduce the occurrence of postoperative GERD.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.