Evidence map›Paper›PMID 34475575›Full record

ArticleThe British journal of psychiatry : the journal of mental science2021

Using epidemiological evidence to forecast population need for early treatment programmes in mental health: a generalisable Bayesian prediction methodology applied to and validated for first-episode psychosis in England.

Keltie McDonald, Tao Ding, Hannah Ker, Thandiwe Rebecca Dliwayo, David P J Osborn, Pia Wohland, Jeremy W Coid, Paul French, Peter B Jones, Gianluca Baio and 1 more

Abstract read
In one paragraph

Article in The British journal of psychiatry : the journal of mental science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  9. The social determinants of mental health and disorder: evidence, prevention and recommendations.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024
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  10. Some priorities in targeting social determinants to achieve prevention of mental disorders.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Keltie McDonaldDivision of Psychiatry, University College London, UK.ORCID 0000-0002-0204-9049
Tao DingDepartment of Statistical Sciences, University College London, UK.
Hannah KerDivision of Psychiatry, University College London, UK.
Thandiwe Rebecca DliwayoDivision of Psychiatry, University College London, UK.
David P J OsbornDivision of Psychiatry, University College London, UK.ORCID 0000-0003-2519-1539
Pia WohlandSchool of Earth and Environmental Sciences, University of Queensland, Australia; Hull-York Medical School, University of Hull, UK.
Jeremy W CoidMental Health Center and Psychiatric Laboratory, The State Key Laboratory of Biotherapy, West China Hospital of Sichuan University, China.ORCID 0000-0002-9480-0257
Paul FrenchFaculty of Health, Psychology and Social Care, Manchester Metropolitan University, UK.ORCID 0000-0003-4300-387X
Peter B JonesDepartment of Psychiatry, University of Cambridge, UK.
Gianluca BaioDepartment of Statistical Sciences, University College London, UK.
James B KirkbrideDivision of Psychiatry, University College London, UK.ORCID 0000-0003-3401-0824

Funding

Wellcome Trust 101272
6 · The paper itself

Abstract

Background: Mental health policy makers require evidence-based information to optimise effective care provision based on local need, but tools are unavailable. Aims: To develop and validate a population-level prediction model for need for early intervention in psychosis (EIP) care for first-episode psychosis (FEP) in England up to 2025, based on epidemiological evidence and demographic projections. Method: We used Bayesian Poisson regression to model small-area-level variation in FEP incidence for people aged 16-64 years. We compared six candidate models, validated against observed National Health Service FEP data in 2017. Our best-fitting model predicted annual incidence case-loads for EIP services in England up to 2025, for probable FEP, treatment in EIP services, initial assessment by EIP services and referral to EIP services for 'suspected psychosis'. Forecasts were stratified by gender, age and ethnicity, at national and Clinical Commissioning Group levels. Results: A model with age, gender, ethnicity, small-area-level deprivation, social fragmentation and regional cannabis use provided best fit to observed new FEP cases at national and Clinical Commissioning Group levels in 2017 (predicted 8112, 95% CI 7623-8597; observed 8038, difference of 74 [0.92%]). By 2025, the model forecasted 11 067 new treated cases per annum (95% CI 10383-11740). For every 10 new treated cases, 21 and 23 people would be assessed by and referred to EIP services for suspected psychosis, respectively. Conclusions: Our evidence-based methodology provides an accurate, validated tool to inform clinical provision of EIP services about future population need for care, based on local variation of major social determinants of psychosis.

Indexed as

Early Medical InterventionMental Health ServicesNeeds AssessmentAdolescentAdultBayes TheoremEnglandFemaleForecastingHumansMaleMiddle AgedPsychotic DisordersReferral and ConsultationReproducibility of ResultsState MedicineBayesian statisticsepidemiologyhealth services researchpredictionPsychotic disorders

Identifiers

PMID34475575
PMCPMC7611597

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.