Evidence map›Paper›PMID 34475267›Full record

ArticleeNeuro

Photoreceptor cKO of OTX2 Enhances OTX2 Intercellular Transfer in the Retina and Causes Photophobia.

Pasquale Pensieri, Annabelle Mantilleri, Damien Plassard, Takahisa Furukawa, Kenneth L Moya, Alain Prochiantz, Thomas Lamonerie

Open access · goldAbstract read
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Unconventional Secretion, Gate to Homeoprotein Intercellular Transfer.Frontiers in cell and developmental biology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 5 institutions in 2 countries.

Pasquale PensieriUniversité Côte d'Azur, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, Institut de Biologie Valrose, Nice 06108, France.
Annabelle MantilleriUniversité Côte d'Azur, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, Institut de Biologie Valrose, Nice 06108, France.
Damien PlassardPlateforme GenomEast, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch 67404, France.
Takahisa FurukawaLaboratory for Molecular and Developmental Biology, Institute for Protein Research, Osaka University, Osaka 565-0871, Japan.ORCID 0000-0003-4171-220X
Kenneth L MoyaCentre for Interdisciplinary Research in Biology (CIRB), Collège de France, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7241, Institut National de la Santé et de la Recherche Médicale Unité 1050, Paris 75005, France.
Alain ProchiantzCentre for Interdisciplinary Research in Biology (CIRB), Collège de France, Centre National de la Recherche Scientifique, Unité Mixte de Recherche 7241, Institut National de la Santé et de la Recherche Médicale Unité 1050, Paris 75005, France.ORCID 0000-0001-7626-5863
Thomas LamonerieUniversité Côte d'Azur, Centre National de la Recherche Scientifique, Institut National de la Santé et de la Recherche Médicale, Institut de Biologie Valrose, Nice 06108, France thomas.lamonerie@univ-cotedazur.fr.
Institut de Biologie Valrose · FRCentre Interdisciplinaire de Recherche en Biologie · FRCollège de France · FRInstitut de génétique et de biologie moléculaire et cellulaire · FRProtein Research Foundation · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the mature mouse retina,

Indexed as

PhotophobiaRetinal DegenerationAnimalsMiceOtx Transcription FactorsPhotoreceptor CellsRetinaOtx2 protein, mouseOtx Transcription Factorsarrestin-1homeoprotein transfermouseOtx2photoreceptorsretina

Identifiers

PMID34475267
PMCPMC8496205
OpenAlexW3197708787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.