Evidence map›Paper›PMID 34475263›Full record

ArticleeNeuro

Seizure Phenotype and Underlying Cellular Defects in

Alexa Joanna Roemmich, Thy Vu, Tamas Lukacsovich, Charlesice Hawkins, Soleil S Schutte, Diane K O'Dowd

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eNeuro. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Review
  6. Frontiers in molecular neuroscience · 2023
    Review
  7. Functional characterization of aTranslational pediatrics · 2022
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Alexa Joanna RoemmichDepartment of Developmental and Cell Biology, University of California, Irvine, Irvine, California 92697.
Thy VuDepartment of Developmental and Cell Biology, University of California, Irvine, Irvine, California 92697.
Tamas LukacsovichFaculties of Medicine and Natural Sciences, Brain Research Institute, University of Zürich, CH-8057 Zürich, Switzerland.
Charlesice HawkinsOffice of Intramural Training and Education, National Institutes of Health, Bethesda, Maryland 20892.
Soleil S SchutteDepartment of Anesthesiology, University of Florida, Gainesville, Florida 32610.
Diane K O'DowdDepartment of Developmental and Cell Biology, University of California, Irvine, Irvine, California 92697 dkodowd@uci.edu.
University of California, Irvine · USNational Institutes of Health · USUniversity of Florida Health · USUniversity of Zurich · CH

Funding

Functional studies of epilepsy mutations in Drosophila and human iPSC-derived neuR01NS083009 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI O'DOWD, DIANE K · 2014 to 2018
$2.6M
NINDS NIH HHS R01 NS083009
6 · The paper itself

Abstract

Mutations in the voltage-gated sodium channel gene

Indexed as

Epilepsies, MyoclonicEpilepsyAnimalsDrosophilaGABAergic NeuronsHumansMutationNAV1.1 Voltage-Gated Sodium ChannelPhenotypeSeizuresNAV1.1 Voltage-Gated Sodium ChannelSCN1A protein, humanDrosophilaelectrophysiologyepilepsySCN1Asodium channel

Identifiers

PMID34475263
PMCPMC8454921
OpenAlexW3197239872

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.