Evidence map›Paper›PMID 34475220›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2021

Reply to Behnam and Klein: Potential role of the His-tag in C-terminal His-tagged SARS-CoV-2 main protease.

Zhe Li, Runduo Liu, Chang-Guo Zhan, Xin Wang, Hai-Bin Luo

Abstract readLetterComment
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Zhe LiGuangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, People's Republic of China.ORCID 0000-0002-9357-6839
Runduo LiuGuangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, People's Republic of China.ORCID 0000-0002-8446-0404
Chang-Guo ZhanMolecular Modeling and Biopharmaceutical Center, College of Pharmacy, University of Kentucky, Lexington, KY 40536; zhan@uky.edu wx8399@ouc.edu.cn luohb77@mail.sysu.edu.cn.ORCID 0000-0002-4128-7269
Xin WangCenter for Innovative Marine Drug Screening & Evaluation, School of Medicine and Pharmacy, Ocean University of China, Qingdao 266100, China; zhan@uky.edu wx8399@ouc.edu.cn luohb77@mail.sysu.edu.cn.ORCID 0000-0001-7467-6060
Hai-Bin LuoGuangdong Provincial Key Laboratory of New Drug Design and Evaluation, School of Pharmaceutical Sciences, Sun Yat-Sen University, Guangzhou 510006, People's Republic of China; zhan@uky.edu wx8399@ouc.edu.cn luohb77@mail.sysu.edu.cn.ORCID 0000-0002-2163-0509

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19SARS-CoV-2Antiviral AgentsEndopeptidasesHumansPeptide HydrolasesAntiviral AgentsEndopeptidasesPeptide Hydrolases

Identifiers

PMID34475220
PMCPMC8433544

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.