ArticlePain management nursing : official journal of the American Society of Pain Management Nurses2022
Association of Hypertension with Knee Pain Severity Among People with Knee Osteoarthritis.
Article in Pain management nursing : official journal of the American Society of Pain Management Nurses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 21 citations in OpenAlex.
- Effects of blood pressure and antihypertensive drugs on osteoarthritis: a mendelian randomized study.Aging clinical and experimental research · 2023Trial
- Metabolic disorders and osteoarthritis: novel insights into pathological mechanisms and therapeutic strategies.Life medicine · 2026Review
- Sarcopenia and physical performance among older adults with increased body mass index and falls.Scientific reports · 2026Article
- Can Certain Antihypertensives Prolong the Efficacy of Hyaluronic Acid Injections in Patients with Osteoarthritis of the Knee? Post Hoc Analysis of a Prospective Observational Trial (PRESAGE).Journal of clinical medicine · 2026Article
- Associations of Arterial Blood Pressure With Radiographic Knee Osteoarthritis and Pain Sensitivity in Middle-Aged and Older Adults.European journal of pain (London, England) · 2026Article
- Association of blood pressure with knee pain progression over 4 years in middle-aged and elderly individuals with or at risks for osteoarthritis: data from the Osteoarthritis Initiative.Clinical rheumatology · 2026Article
- The Relationship Between Metabolic Syndrome and Pain Catastrophizing in Psoriatic Arthritis.Rheumatology and therapy · 2025Article
- The Coexistence of Hypertension and Arthritis Was Not Associated with Pain Severity in Community-Dwelling Older Adults in the United States.Healthcare (Basel, Switzerland) · 2025Article
- A Longitudinal Decline in Walking Speed Is Linked with Coexisting Hypertension and Arthritis in Community-Dwelling Older Adults.Journal of clinical medicine · 2024Article
- Blood pressure is associated with knee pain severity in middle-aged and elderly individuals with or at risks for osteoarthritis: data from the Osteoarthritis Initiative.BMC musculoskeletal disorders · 2024Article
- Causal relationship between modifiable risk factors and knee osteoarthritis: a Mendelian randomization study.Frontiers in medicine · 2024Article
- Antihypertensive drug-associated adverse events in osteoarthritis: a study of a large real-world sample based on the FAERS database.Frontiers in pharmacology · 2024Article
- Causal relationship between diet and knee osteoarthritis: A Mendelian randomization analysis.PloS one · 2024Article
- Do Individualized Patient-Specific Situations Predict the Progression Rate and Fate of Knee Osteoarthritis? Prediction of Knee Osteoarthritis.Journal of clinical medicine · 2023Article
- Prevalence of pain in community-dwelling older adults with hypertension in the United States.Scientific reports · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
purposeTo examine the association of hypertension with knee pain severity in individuals with knee osteoarthritis (OA).
designCross-sectional study of baseline data collected by the Osteoarthritis Initiative.
methodsParticipants with knee OA (N=1,363) were categorized into four groups based on blood pressure (BP): 1) systolic < 120 mm HG and diastolic < 80 mm Hg; 2) 120 ≤ systolic < 130 mm Hg and diastolic < 80 mm Hg; 3) 130 ≤ systolic < 140 mm Hg or 80 ≤ diastolic < 90 mm Hg; 4) systolic ≥ 140 mm Hg or diastolic ≥ 90 mm Hg. OA knee pain severity was measured by Pain subscale of Western Ontario and McMaster Universities Osteoarthritis Index in the past 48 hours, Pain subscale of Knee Injury and Osteoarthritis Outcome Score (KOOS) in the past 7 days, and numeric rating scale (NRS) in the past 30 days. Linear regression was used to examine the relationship between hypertension and knee pain severity.
resultsCompared with the normal BP group, individuals with stage 2 hypertension reported significantly higher OA knee pain severity by KOOS in the past 7 days (β=-2.05 [95% CI -4.09, -0.01], p=0.049) and by NRS in the past 30 days (β=0.31 [95% CI 0.01, 0.62], p=0.045) after adjustments for demographic and medical factors.
conclusionsHypertension was associated with higher OA knee pain severity in individuals with knee OA. CLINICAL IMPLICATIONS: Nurses can recommend adjunctive non-pharmacological treatments and adherence strategies to help control hypertension, which may help decrease OA knee pain.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.