Evidence map›Paper›PMID 34474598›Full record

Trial reportAutism : the international journal of research and practice2022

A preliminary randomized, controlled trial of executive function training for children with autism spectrum disorder.

Susan Faja, Tessa Clarkson, Rachel Gilbert, Akshita Vaidyanathan, Gabriella Greco, M Rosario Rueda, Lina M Combita, Kate Driscoll

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Autism : the international journal of research and practice, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Trial
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Susan FajaBoston Children's Hospital, USA.ORCID 0000-0001-6876-3643
Tessa ClarksonBoston Children's Hospital, USA.
Rachel GilbertBoston Children's Hospital, USA.
Akshita VaidyanathanBoston Children's Hospital, USA.
Gabriella GrecoBoston Children's Hospital, USA.
M Rosario RuedaUniversity of Granada, Spain.
Lina M CombitaUniversity of Granada, Spain.
Kate DriscollBoston Children's Hospital, USA.
Boston Children's Hospital · USUniversidad de Granada · ES

Funding

Genetic Analysis and Manipulation Core (GAEC)P50HD105351 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI SCOTT Loren POMEROY, MUSTAFA SAHIN · 2021 to 2026
$9.4M
Electrophysiological Response to Executive Control Training in AutismR00HD071966 · NICHD · BOSTON CHILDREN'S HOSPITAL · PI FAJA, SUSAN · 2014 to 2016
$718k
NICHD NIH HHS P50 HD105351NICHD NIH HHS R00 HD071966
6 · The paper itself

Abstract

lay abstractExecutive function, which is a set of thinking skills that includes stopping unwanted responses, being flexible, and remembering information needed to solve problems, is a challenge for many children on the autism spectrum. This study tested whether executive function could be improved with a computerized executive function training program under the guidance of a coach who reinforced the use of executive function skills. Seventy children with autism spectrum disorder from age 7 to 11 years of age participated in the study. They were randomly assigned to receive training or to a waiting group. The tests most likely to determine whether the training may be effective were chosen from a larger battery before the study started and included one task measuring brain responses, two measures of executive function in the lab, and a parent questionnaire. Changes in social functioning and repetitive behaviors were also explored. All children assigned to training completed the program and families generally reported the experience was positive. Brain responses of the training group changed following training, but not within the waiting group during a similar time period. Children who received training did not exhibit behavioral changes during the two the lab-based tasks. Parent report on questionnaires indicated that neither group showed a significant change in their broad use of executive function in other settings. Yet, children who received training were reported to have fewer restricted and repetitive behaviors following training. These initial findings suggest that short executive function training activities are feasible and may improve some functioning of school-aged children on the autism spectrum.

Indexed as

Autism Spectrum DisorderChildCognitionExecutive FunctionHumansSocial Adjustmentautism spectrum disorderclinical trialevent-related potentialexecutive functioninhibition

Identifiers

PMID34474598
PMCPMC8813874
OpenAlexW3198128226

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.