Observational studyEndocrinology and metabolism (Seoul, Korea)2021
Thyroid Hormone Profile and Its Prognostic Impact on the Coronavirus Disease 2019 in Korean Patients.
Observational study in Endocrinology and metabolism (Seoul, Korea), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 36 citations in OpenAlex.
- The prevalence of thyroid disorders in COVID-19 patients: a systematic review and meta-analysis.BMC endocrine disorders · 2024Pooled it
- Thyroid function during COVID-19 and post-COVID complications in adults: a systematic review.Frontiers in endocrinology · 2024Pooled it
- Thyroxine changes in COVID-19 pandemic: A systematic review and meta-analysis.Frontiers in endocrinology · 2023Pooled it
- Association of thyroid dysfunction and COVID-19: A systematic review and meta-analysis.Frontiers in endocrinology · 2022Pooled it
- The Association Between COVID-19 and Thyroxine Levels: A Meta-Analysis.Frontiers in endocrinology · 2021Pooled it
- Emerging evidence from China indicates SARS- COV-2 may be associated with newly diagnosed Hashimoto's thyroiditis: a clinical study of 54 patients with COVID-19 complicated by newly diagnosed disease.Frontiers in endocrinology · 2026Article
- Article
- Thyroid Function in the Time of COVID-19: A Systematic Review of Disease Progression and Vaccination Effect.International journal of endocrinology and metabolism · 2024Article
- Thyroid Stimulating Hormone as a Possible Additional COVID-19 Outcome Marker.Medicina (Kaunas, Lithuania) · 2024Article
- Association between thyroid function and prognosis of severe COVID-19 among patients with SARS-CoV-2 infection: a retrospective cohort study in China.Frontiers in endocrinology · 2024Article
- The prognostic utility of serum thyrotropin in hospitalized Covid-19 patients: statistical and machine learning approaches.Endocrine · 2023Article
- The Influence of SARS-CoV-2 Infection on the Thyroid Gland.Biomedicines · 2023Review
- Transient low T3 syndrome in patients with COVID-19: a new window for prediction of disease severity.Frontiers in endocrinology · 2023Article
- Thyrotropin Levels in Patients with Coronavirus Disease 2019: Assessment during Hospitalization and in the Medium Term after Discharge.Life (Basel, Switzerland) · 2022Article
- The New Entity of Subacute Thyroiditis amid the COVID-19 Pandemic: From Infection to Vaccine.Diagnostics (Basel, Switzerland) · 2022Review
- COVID-19 and thyroid function: What do we know so far?Frontiers in endocrinology · 2022Review
- Potential of Endogenous Oxytocin in Endocrine Treatment and Prevention of COVID-19.Frontiers in endocrinology · 2022Review
- The Association Between FT3 With the Outcome and Inflammation/Coagulopathy/Fibrinolysis of COVID-19.Frontiers in endocrinology · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundData on the association between coronavirus disease 2019 (COVID-19) and thyroid have been reported, including overt thyrotoxicosis and suppression of thyroid function. We aimed to evaluate the thyroid hormone profile and its association with the prognosis of COVID-19 in Korean patients.
methodsThe clinical data of 119 patients with COVID-19, admitted in the Myongji Hospital, Goyang, South Korea, were retrospectively evaluated. The thyroid hormone profiles were analyzed and compared based on disease severity (non-severe disease vs. severe to critical disease). Clinical outcomes were analyzed according to the tertiles of thyroid hormones.
resultsOf the 119 patients, 76 (63.9%) were euthyroid, and none presented with overt thyroid dysfunction. Non-thyroidal illness syndrome was the most common manifestation (18.5%), followed by subclinical thyrotoxicosis (14.3%) among patients with thyroid dysfunction. Thyroid stimulating hormone (TSH) and triiodothyronine (T3) levels were significantly lower in patients with severe to critical disease than in those with non-severe disease (P<0.05). Patients in the lowest T3 tertile (<0.77 ng/mL) had higher rates of mechanical ventilation, intensive care unit admission, and death than those in the middle and highest (>1.00 ng/mL) T3 tertiles (P<0.05). COVID-19 patients in the lowest T3 tertile were independently associated with mortality (hazard ratio, 5.27; 95% confidence interval, 1.09 to 25.32; P=0.038) compared with those in the highest T3 tertile.
conclusionThyroid dysfunction is common in COVID-19 patients. Changes in serum TSH and T3 levels may be important markers of disease severity in COVID-19. Decreased T3 levels may have a prognostic significance in COVID-19 related outcome.
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