ArticleBiosensors & bioelectronics2021
Decentralized vitamin C & D dual biosensor chip: Toward personalized immune system support.
Article in Biosensors & bioelectronics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 24 citations in OpenAlex.
- A fully integrated smart ring for daily biochemical monitoring.Nature communications · 2026Article
- Computational Insights Into Smart Bioelectronics in Digital Health Care (2020-2024): Topic Modeling Study.JMIR medical informatics · 2026Review
- Review
- Bioelectroanalytical Technologies for Advancing the Frontiers To Democratize Personalized Desired Health.Analytical chemistry · 2025Review
- Parallel assembly of dual-electrochemical cell: a novel approach for simultaneous multiplexed sensing analysis.Mikrochimica acta · 2025Article
- Electrochemical sensing of B-complex vitamins: current challenges and future prospects with microfluidic integration.RSC advances · 2024Review
- Therapeutic Effects of Vitamins and Nutritional Supplements on Sinusitis: A Narrative Review.Nutrition and metabolic insights · 2024Review
Corrections and comments
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Combating the ongoing COVID-19 pandemic has put the spotlight on nutritional support of the immune system through consumption of vitamins C and D. Accordingly, there are urgent demands for an effective on-the-spot multi-vitamin self-testing platform that monitors the levels of these immune-supporting micronutrients for guiding precision nutrition recommendations. Herein, we present a compact bioelectronic dual sensor chip aimed at frequent on-the-spot simultaneous monitoring of the salivary vitamin C and D dynamics. The new bioelectronic chip combines a new electrocatalytic vitamin C amperometric assay along with competitive vitamin D immunoassay on neighboring electrodes, to perform selective and cross-talk free detection of both vitamins in a 10-μL saliva sample within 25 min. The distinct vitamin C or D temporal profiles obtained for different individuals after vitamin supplementation indicate the potential of the new bioelectronic chip strategy for enhancing personalized nutrition towards guiding dietary interventions to meet individual nutrition needs and promote immune system health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.