Evidence map›Paper›PMID 34473763›Full record

ArticlePloS one2021

Bioengineered phytomolecules-capped silver nanoparticles using Carissa carandas leaf extract to embed on to urinary catheter to combat UTI pathogens.

Haajira Beevi Habeeb Rahuman, Ranjithkumar Dhandapani, Velmurugan Palanivel, Sathiamoorthi Thangavelu, Ragul Paramasivam, Saravanan Muthupandian

Abstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed.

  1. Species-Specific Stress Responses to Selenium Nanoparticles inNanomaterials (Basel, Switzerland) · 2025
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  3. Adhesion Study ofEthiopian journal of health sciences · 2025
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  6. Investigation of Antimicrobial and Antioxidant Properties ofJournal of pharmacy & bioallied sciences · 2024
    Article
  7. Enhancing Dental Alginate withGels (Basel, Switzerland) · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Review
  12. Immunomodulation in age-related disorders and nanotechnology interventions.Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology · 2023
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Haajira Beevi Habeeb RahumanDepartment of Microbiology, Science Campus, Alagappa University, Karaikudi, Tamilnadu, India.
Ranjithkumar DhandapaniDepartment of Microbiology, Science Campus, Alagappa University, Karaikudi, Tamilnadu, India.ORCID 0000-0003-0472-8077
Velmurugan PalanivelCentre for for Material Engineering and Regenerative Medicine Bharath Institute of Higher Education, Chennai, India.
Sathiamoorthi ThangaveluDepartment of Microbiology, Science Campus, Alagappa University, Karaikudi, Tamilnadu, India.
Ragul ParamasivamChimertech Innovations LLP, Tamilnadu Veterinary and Animal Science University, Chennai, India.ORCID 0000-0003-1316-8526
Saravanan MuthupandianDivision of Biomedical sciences, College of Health Sciences, School of Medicine, Mekelle, Ethiopia.ORCID 0000-0002-1480-3555

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rising incidents of urinary tract infections (UTIs) among catheterized patients is a noteworthy problem in clinic due to their colonization of uropathogens on abiotic surfaces. Herein, we have examined the surface modification of urinary catheter by embedding with eco-friendly synthesized phytomolecules-capped silver nanoparticles (AgNPs) to prevent the invasion and colonization of uropathogens. The preliminary confirmation of AgNPs production in the reaction mixture was witnessed by the colour change and surface resonance plasmon (SRP) band at 410nm by UV-visible spectroscopy. The morphology, size, crystalline nature, and elemental composition of attained AgNPs were further confirmed by the transmission electron microscopy (TEM), selected area electron diffraction (SAED), X-ray diffraction (XRD) technique, Scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS). The functional groups of AgNPs with stabilization/capped phytochemicals were detected by Fourier-transform infrared spectroscopy (FTIR). Further, antibiofilm activity of synthesized AgNPs against biofilm producers such as Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa were determined by viability assays and micrographically. AgNPs coated and coating-free catheters performed to treat with bacterial pathogen to analyze the mat formation and disruption of biofilm formation. Synergistic effect of AgNPs with antibiotic reveals that it can enhance the activity of antibiotics, AgNPs coated catheter revealed that, it has potential antimicrobial activity and antibiofilm activity. In summary, C. carandas leaf extract mediated synthesized AgNPs will open a new avenue and a promising template to embed on urinary catheter to control clinical pathogens.

Indexed as

Anti-Bacterial AgentsApocynaceaeBiofilmsCiprofloxacinEscherichia coliEscherichia coli InfectionsGentamicinsGreen Chemistry TechnologyHumansMetal NanoparticlesMicrobial Sensitivity TestsParticle SizePhytochemicalsPlant ExtractsPlant LeavesPseudomonas aeruginosaAnti-Bacterial AgentsCiprofloxacinGentamicinsPhytochemicalsPlant ExtractsSilverTrimethoprim

Identifiers

PMID34473763
PMCPMC8412375

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.