Evidence map›Paper›PMID 34473757›Full record

ArticlePloS one2021

Migration in Namibia and its association with HIV acquisition and treatment outcomes.

Andrea Low, Karam Sachathep, George Rutherford, Anne-Marie Nitschke, Adam Wolkon, Karen Banda, Leigh Ann Miller, Chelsea Solmo, Keisha Jackson, Hetal Patel and 3 more

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Andrea LowICAP at Columbia University, Mailman School of Public Health, Columbia University, New York, NY, United States of America.ORCID 0000-0002-7088-4556
Karam SachathepICAP at Columbia University, Mailman School of Public Health, Columbia University, New York, NY, United States of America.
George RutherfordInstitute for Global Health Sciences, University of California, San Francisco, CA, United States of America.
Anne-Marie NitschkeMinistry of Health and Social Services, Windhoek, Namibia.
Adam WolkonCenters for Disease Control and Prevention, Windhoek, Namibia.
Karen BandaInstitute for Global Health Sciences, University of California, San Francisco, CA, United States of America.
Leigh Ann MillerCenters for Disease Control and Prevention, Windhoek, Namibia.
Chelsea SolmoICAP at Columbia University, Mailman School of Public Health, Columbia University, New York, NY, United States of America.
Keisha JacksonDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Center for Global Health, Atlanta, GA, United States of America.
Hetal PatelDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Center for Global Health, Atlanta, GA, United States of America.
Stephen McCrackenDivision of Global HIV and Tuberculosis, Centers for Disease Control and Prevention, Center for Global Health, Atlanta, GA, United States of America.
Sally FindleyICAP at Columbia University, Mailman School of Public Health, Columbia University, New York, NY, United States of America.
Nicholus MutendaMinistry of Health and Social Services, Windhoek, Namibia.
Columbia University · USCenters for Disease Control and Prevention · USMinistry of Health and Social Services · NAUniversity of California, San Francisco · US

Funding

CGH CDC HHS U2G GH001226
6 · The paper itself

Abstract

backgroundIn the 21st century, understanding how population migration impacts human health is critical. Namibia has high migration rates and HIV prevalence, but little is known about how these intersect. We examined the association between migration and HIV-related outcomes using data from the 2017 Namibia Population-based HIV Impact Assessment (NAMPHIA). METHODS AND

findingsThe NAMPHIA survey selected a nationally representative sample of adults in 2017. All adults aged 15-64 years were invited to complete an interview and home-based HIV test. Recent infection (<130 days) was measured using HIV-1 LAg avidity combined with viral load (>1000 copies/mL) and antiretroviral analyte data. Awareness of HIV status and antiretroviral use were based on self-report and/or detectable antiretrovirals in blood. Viremia was defined as having a viral load ≥1000 copies/mL, including all participants in the denominator regardless of serostatus. We generated community viremia values as a weighted proportion at the EA level, excluding those classified as recently infected. Significant migrants were those who had lived outside their current region or away from home >one month in the past three years. Recent cross-community in-migrants were those who had moved to the community <two years ago. Separate analyses were done to compare significant migrants to non-migrants and recent cross-community in-migrants to those who in-migrated >two years ago to determine the association of migration and timing with recent infection or viral load suppression (VLS). All proportions are weighted. Of eligible adults, we had HIV results and migration data on 9,625 (83.9%) of 11,474 women and 7,291 (73.0%) of 9,990 men. Most respondents (62.5%) reported significant migration. Of cross-community in-migrants, 15.3% were recent. HIV prevalence was 12.6% and did not differ by migration status. Population VLS was 77.4%. Recent cross-community in-migration was associated with recent HIV infection (aOR: 4.01, 95% CI 0.99-16.22) after adjusting for community viremia. Significant migration (aOR 0.73, 95% CI: 0.55-0.97) and recent cross-community in-migration (aOR 0.57, 95% CI: 0.35-0.92) were associated with lower VLS, primarily due to lack of awareness of HIV infection. The study was limited by lack of precise data on trajectory of migration.

conclusionsDespite a high population-level VLS, Namibia still has migrant populations that are not accessing effective treatment for HIV. Targeting migrants with effective prevention and testing programs in communities with viremia could enable further epidemic control.

Indexed as

Emigration and ImmigrationAdolescentAdultAnti-Retroviral AgentsCross-Sectional StudiesFamily CharacteristicsFemaleHIV-1HIV InfectionsHumansMaleMiddle AgedNamibiaPrevalenceSelf ReportTransients and MigrantsAnti-Retroviral Agents

Identifiers

PMID34473757
PMCPMC8412347
OpenAlexW3198698979

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.