Observational studyPloS one2021
Risk factors associated with the development of delirium in general ICU patients. A prospective observational study.
Observational study in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Critical care delirium: prevention, identification and management: a narrative review.Anaesthesia · 2026Review
- Article
- Psychometric Properties of the Persian Version of the Delirium Care Self-Efficacy Scale for Intensive Care Unit Nurses: A Methodological Study.Nursing open · 2026Article
- Observational
- Sleep Quality and Delirium Occurrence in Intensive Care Unit Patients: A Prospective Observational Study.Nursing in critical care · 2026Observational
- A machine learning-based prediction model for delirium risk in malnourished elderly ICU patients with SHAP interpretability.Frontiers in nutrition · 2026Article
- Validation of the confusion assessment method for intensive care.Open medicine (Warsaw, Poland) · 2026Article
- Readmissions to a Surgical Intensive Care Unit: Incidence and Risk Stratification for Personalized Patient Care.Journal of personalized medicine · 2025Article
- Improving Intensive Care Unit Nurses' Delirium Assessment Performance Through a Multimodal Educational Intervention.Nursing in critical care · 2025Article
- Incidence of Delirium in ICU Patients With and Without COVID-19 in a Costa Rican Hospital.Cureus · 2024Article
- Patient Outcomes and Management Strategies for Intensive Care Unit (ICU)-Associated Delirium: A Literature Review.Cureus · 2024Review
- Functional independence, frailty and perceived quality of life in patients who developed delirium during ICU stay: a prospective cohort study.European journal of medical research · 2023Observational
- Modern Sedation and Analgesia Strategies in Neurocritical Care.Current neurology and neuroscience reports · 2023Review
- Review
- Risk factors for delirium after surgery for craniocerebral injury in the neurosurgical intensive care unit.World journal of clinical cases · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveWe aimed to analyze risk factors related to the development of delirium, aiming for early intervention in patients with greater risk. MATERIAL AND
methodsObservational study, including prospectively collected patients treated in a single general ICU. These were classified into two groups, according to whether they developed delirium or not (screening performed using CAM-ICU tool). Demographics and clinical data were analyzed. Multivariate logistic regression analyses were performed to quantify existing associations.
results1462 patients were included. 93 developed delirium (incidence: 6.3%). These were older, scored higher on the Clinical Frailty Scale, on the risk scores on admission (SAPS-3 and SOFA), and had a greater number of organ failures (OF). We observed more incidence of delirium in patients who (a) presented more than two OF (20.4%; OR 4.9; CI95%: 2.9-8.2), and (b) were more than 74 years old albeit having <2 OF (8.6%; OR 2.1; CI95%: 1.3-3.5). Patients who developed delirium had longer ICU and hospital length-of-stays and a higher rate of readmission.
conclusionsThe highest risk observed for developing delirium clustered in patients who presented more than 2 OF and patients over 74 years old. The detection of patients at high risk for developing delirium could imply a change in management and improved quality of care.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.