Evidence map›Paper›PMID 34473409›Full record

ArticleJournal of the International AIDS Society2021

Stakeholder efforts to mitigate antiretroviral therapy interruption among people living with HIV during the COVID-19 pandemic in China: a qualitative study.

Yinghui Sun, Yuewei Zhan, Hui Li, Tanwei Yuan, Yanxiao Gao, Bowen Liang, Anping Feng, Peiyang Li, Weiran Zheng, Thomas Fitzpatrick and 3 more

Open access · goldAbstract read
In one paragraph

Article in Journal of the International AIDS Society, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 2 pooled it
1.0field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 5 institutions in 4 countries.

Yinghui SunSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, China.ORCID 0000-0001-9946-9877
Yuewei ZhanSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, China.ORCID 0000-0002-4855-1800
Hui LiShizhong District Center for Disease Control and Prevention, Jinan, China.ORCID 0000-0003-2351-9377
Tanwei YuanSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, China.ORCID 0000-0001-7387-6327
Yanxiao GaoSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, China.ORCID 0000-0002-3552-052X
Bowen LiangSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, China.ORCID 0000-0001-6259-7373
Anping FengSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, China.ORCID 0000-0002-1923-8786
Peiyang LiSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, China.ORCID 0000-0001-5964-9136
Weiran ZhengSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, China.
Thomas FitzpatrickDepartment of Internal Medicine, University of Washington, Seattle, Washington, USA.ORCID 0000-0002-0852-7291
Dan WuLondon School of Hygiene & Tropical Medicine, London, UK.ORCID 0000-0003-0415-5467
Xinyi ZhaiDanlan Goodness, BlueCity Holdings Ltd., Beijing, China.
Huachun ZouSchool of Public Health (Shenzhen), Sun Yat-sen University, Shenzhen, China.ORCID 0000-0002-8161-7576
Sun Yat-sen University · CNChina National Chemical Corporation (China) · CNLondon School of Hygiene & Tropical Medicine · GBShandong Center for Disease Control and Prevention · CNUniversity of Washington · US

Funding

Fundamental Research Funds for the Central Universities 58000-31620005High Level Project of Medicine in Longhua, Shenzhen: Shenzhen Municipal Health Commission HLPM201907020105High-Level Talents of Guangdong Province: High-Level Talents of Guangdong Province 2019TQ05Y230National Key Research and Development Program of China: National Basic Research Program of China (973 Program) 2020YFC0840900National Science and Technology Major Project of China: Ministry of Science and Technology of the People's Republic of China 2018ZX10721102Natural Science Foundation of China Excellent Young Scientists Fund: National Natural Science Foundation of China 82022064Natural Science Foundation of China International/Regional Research Collaboration Project: National Natural Science Foundation of China 72061137001Natural Science Foundation of China Young Scientist Fund: National Natural Science Foundation of China 81703278Sanming Project of Medicine in Shenzhen SZSM201811071Shenzhen Science and Technology Innovation Commission Basic Research Program: Shenzhen Science and Technology Innovation Committee JCYJ20190807155409373
6 · The paper itself

Abstract

introductionThe COVID-19 pandemic has affected antiretroviral therapy (ART) continuity among people living with HIV (PLHIV) worldwide. We conducted a qualitative study to explore barriers to ART maintenance and solutions to ART interruption when stringent COVID-19 control measures were implemented in China, from the perspective of PLHIV and relevant key stakeholders.

methodsBetween 11 February and 15 February 2020, we interviewed PLHIV, community-based organization (CBO) workers, staff from centres for disease control and prevention (CDC) at various levels whose work is relevant to HIV care (CDC staff), HIV doctors and nurses and drug vendors from various regions in China. Semi-structured interviews were conducted using a messaging and social media app. Challenges and responses relevant to ART continuity during the COVID-19 pandemic were discussed. Themes were identified by transcript coding and mindmaps.

resultsSixty-four stakeholders were recruited, including 16 PLHIV, 17 CBO workers, 15 CDC staff, 14 HIV doctors and nurses and two drug vendors. Many CDC staff, HIV doctors and nurses responsible for ART delivery and HIV care were shifted to COVID-19 response efforts. Barriers to ART maintenance were (a) travel restrictions, (b) inadequate communication and bureaucratic obstacles, (c) shortage in personnel, (d) privacy concerns, and (e) insufficient ART reserve. CBO helped PLHIV maintain access to ART through five solutions identified from thematic analysis: (a) coordination to refill ART from local CDC clinics or hospitals, (b) delivery of ART by mail, (c) privacy protection measures, (d) mental health counselling, and (e) providing connections to alternative sources of ART. Drug vendors contributed to ART maintenance by selling out-of-pocket ART.

conclusionsSocial and institutional disruption from COVID-19 contributed to increased risk of ART interruption among PLHIV in China. Collaboration among key stakeholders was needed to maintain access to ART, with CBO playing an important role. Other countries facing ART interruption during current or future public health emergencies may learn from the solutions employed in China.

Indexed as

Continuity of Patient CareCOVID-19Health Services AccessibilityAdultAnti-Retroviral AgentsAntiretroviral Therapy, Highly ActiveChinaFemaleHIV InfectionsHumansMalePandemicsQualitative ResearchSARS-CoV-2Stakeholder ParticipationAnti-Retroviral Agentsantiretroviral therapyantiretroviral therapy maintenancecommunity-based organizationCOVID-19HIVpeople living with HIV

Identifiers

PMID34473409
PMCPMC8412021
OpenAlexW3197327527

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.