Evidence map›Paper›PMID 34472888›Full record

ArticleJournal of abnormal psychology2021

The associations between polygenic risk, sensation seeking, social support, and alcohol use in adulthood.

Jinni Su, Sally I-Chun Kuo, Fazil Aliev, Grace Chan, Howard J Edenberg, Chella Kamarajan, Vivia V McCutcheon, Jacquelyn L Meyers, Marc Schuckit, Jay Tischfield and 1 more

Open access · greenAbstract read
In one paragraph

Article in Journal of abnormal psychology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. DNA Methylation in Alcohol Use Disorder.International journal of molecular sciences · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Jinni SuDepartment of Psychology.ORCID 0000-0002-9767-1489
Sally I-Chun KuoDepartment of Psychology.ORCID 0000-0002-6192-1001
Fazil AlievDepartment of Psychology.ORCID 0000-0001-8357-4699
Grace ChanDepartment of Psychiatry.ORCID 0000-0002-1257-6889
Howard J EdenbergDepartment of Biochemistry and Molecular Biology.ORCID 0000-0003-0344-9690
Chella KamarajanDepartment of Psychiatry.ORCID 0000-0003-2291-6880
Vivia V McCutcheonDepartment of Psychiatry.
Jacquelyn L MeyersDepartment of Psychiatry.
Marc SchuckitDepartment of Psychiatry.
Jay TischfieldDepartment of Genetics.
Danielle M DickDepartment of Psychology.
Washington University in St. Louis · US

Funding

Subject CollectionU10AA008401 · NIAAA · SUNY DOWNSTATE MEDICAL CENTER · PI BERNICE PORJESZ · 1989 to 2026
$162.7M
National Centralized Repository for Alzheimer's Disease and Related Dementias (NCRAD)U24AG021886 · NIA · INDIANA UNIV-PURDUE UNIV AT INDIANAPOLIS · PI TATIANA M. FOROUD · 2002 to 2026
$119.8M
NIAAA NIH HHS U10 AA008401NIA NIH HHS U24 AG021886
6 · The paper itself

Abstract

Genetic predispositions play an important role in alcohol use. Understanding the psychosocial mechanisms through which genetic risk unfolds to influence alcohol use outcomes is critical for identifying modifiable targets and developing prevention and intervention efforts. In this study, we examined the role of sensation seeking and social support from family and friends in linking genetic risk to alcohol use. We also examined the role of social support in moderating the associations between genetic risk and sensation seeking and alcohol use. Data were drawn from a sample of 2,836 European American adults from the Collaborative Study on the Genetics of Alcoholism (46% male, mean age = 35.65, standard deviation [

Indexed as

Alcohol DrinkingAlcoholismAdultFemaleHumansMaleMultifactorial InheritanceSensationSocial Support

Identifiers

PMID34472888
PMCPMC10882995
OpenAlexW3197090725

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.