ArticleInternational wound journal2022
An injectable metal nanoparticle containing cellulose derivative-based hydrogels: Evaluation of antibacterial and in vitro-vivo wound healing activity in children with burn injuries.
Article in International wound journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Innovative Hydroxyapatite-Hydrogel Composites for Cartilage Regeneration.Gels (Basel, Switzerland) · 2026Review
- Cellulose and Its Derivatives-Based Skin Dressings: Design, Smart Advances and Applications.Pharmaceutics · 2026Review
- Protein-Directed Nucleation and Stabilization of Ultrasmall Silver Nanoparticles Within BSA Hydrogels.Gels (Basel, Switzerland) · 2026Article
- Smart Polymer-Derived Injectable Hydrogels: Current Status and Future Perspectives.ACS polymers Au · 2025Review
- Synthesis and characterization of silver nanoparticle-loaded carboxymethylcellulose hydrogels: in vitro and in vivo evaluation of wound healing and antibacterial properties.Cell and tissue banking · 2025Article
- Polymeric Systems as Hydrogels and Membranes Containing Silver Nanoparticles for Biomedical and Food Applications: Recent Approaches and Perspectives.Gels (Basel, Switzerland) · 2025Review
- Injectable nanocomposite hydrogels for targeted intervention in cancer, wound healing, and bone and myocardial tissue engineering.Drug delivery and translational research · 2025Review
- Optimization of Metal-Based Nanoparticle Composite Formulations and Their Application in Wound Dressings.International journal of nanomedicine · 2025Review
- Evolution of Hybrid Hydrogels: Next-Generation Biomaterials for Drug Delivery and Tissue Engineering.Gels (Basel, Switzerland) · 2024Review
- Formulation and Comprehensive Evaluation of Biohybrid Hydrogel Membranes Containing Doxycycline or Silver Nanoparticles.Pharmaceutics · 2023Article
- Article
- Cellulose-Based Metallogels-Part 2: Physico-Chemical Properties and Biological Stability.Gels (Basel, Switzerland) · 2023Review
- A Review of Metal Nanoparticles Embedded in Hydrogel Scaffolds for Wound Healing In Vivo.Gels (Basel, Switzerland) · 2023Review
- Combating Microbial Infections Using Metal-Based Nanoparticles as Potential Therapeutic Alternatives.Antibiotics (Basel, Switzerland) · 2023Review
- Article
- An injectable metal nanoparticle containing cellulose derivative-based hydrogels: Evaluation of antibacterial and in vitro-vivo wound healing activity in children with burn injuries.International wound journal · 2022Article
- An Overview of Cellulose Derivatives-Based Dressings for Wound-Healing Management.Pharmaceuticals (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The preparation of hydrogels for wound healing properties with high antibacterial activities and good biosafety concurrently can be relatively challenging. For addressing these issues, we report on the synthesis and characterisation of a nanocomposite hydrogel dressing by introducing the silver nanoparticles in hydroxypropyl methylcellulose-hydroxyapatite scaffold hydrogel (HMC-HA/AgNPs). The different concentrations of AgNPs in HMC-HA/AgNPs hydrogels were confirmed by swelling ratio, degradation, and gelatin time. The synthesised HMC-HA/AgNPs hydrogels were further characterised using the UV-visible, scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectrum, and X-ray diffraction. The results showed that the novel HMC-HA/AgNPs hydrogel exhibited a porous 3D network and high mechanical properties because of the inter-molecular and intra-molecular interactions. The AgNPs give the HMC-HA hydrogels excellent antibacterial activities against both Staphylococcus aureus and Escherichia coli, without any chemical reductant and cross-linking agent required endows the hydrogel high biocompatibility. More importantly, HMC-HA/AgNPs effectively repaired wound defects in mice models, and wound healing reached 94.5 ± 1.4% within 16 days. The HMC-HA hydrogel with AgNPs showed excellent antimicrobial activity and burn wound healing. Therefore, these HMC-HA/AgNPs hydrogels have great potential as an injectable hydrogel for wound healing activity in children with burn injuries.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.