Evidence map›Paper›PMID 34472573›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2021

Challenges of Assessing Community Mortality Due to Respiratory Viruses in Children Aged Less Than 5 Years.

Mauricio T Caballero, Ashish Satav, Christopher J Gill, Saad B Omer, Rachel C Pieciak, Abdul Momin Kazi, Eric Af Simões, Fernando P Polack

Open access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 7 institutions in 4 countries.

Mauricio T CaballeroFundacion INFANT, Buenos Aires, Argentina.ORCID 0000-0002-4218-5942
Ashish SatavMeditation, AIDS, Health, Addiction & Nutrition (MAHAN) (MAHAN) Trust, Mahatma Gandhi Tribal Hospital Karmagram, Utavali, Tahsil, Dharni, Amravati, India.
Christopher J GillDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, USA.
Saad B OmerYale Institute for Global Health, Yale University, New Haven, Connecticut, USA.
Rachel C PieciakDepartment of Global Health, Boston University School of Public Health, Boston, Massachusetts, USA.
Abdul Momin KaziDepartment of Pediatrics, The Aga Khan University, Karachi, Pakistan.
Eric Af SimõesDepartment of Pediatrics, Section of Infectious Diseases, University of Colorado School of Medicine, and Children's Hospital Colorado, Aurora, Colorado, USA.
Fernando P PolackFundacion INFANT, Buenos Aires, Argentina.
Boston University · USAga Khan University · PKColorado School of Public Health · USConsejo Nacional de Investigaciones Científicas y Técnicas · ARInfant Foundation · ARMeditation De-Addiction Health AIDS Nutrition Trust · INYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

backgroundEstimating the real impact of respiratory syncytial virus (RSV) disease is key for the development of vaccines and treatments. Ascertaining the burden of community mortality due to RSV is challenging due to the lack of primary data. Therefore, conducting observational studies to determine the factors associated with community mortality due to the virus in developing countries is important.

objectiveOur aim in this study was to describe the obstacles, gaps, and challenges that investigators face in low-income, vulnerable regions in 4 developing countries on 3 continents.

resultsThe main obstacles and challenges of ascertaining community mortality due to RSV were defining strategies to consent families for testing before burial, sampling individuals at the household level, supporting bereaved parents with different cultural and religious backgrounds, establishing tailored strategies for studies in challenging settings, and integrating RSV mortality data from nasopharyngeal samples.

conclusionDetailed logistical planning based on population sociodemographic information, grief counseling, staff training, and a multidisciplinary approach with adequate laboratory infrastructure is critical to successful observational community-based RSV studies.

Indexed as

Respiratory Syncytial Virus InfectionsChildHumansNasopharynxRespiratory Syncytial VirusesRisk Factorschallengescommunity mortalityrespiratory syncytial virus

Identifiers

PMID34472573
PMCPMC8411250
OpenAlexW3198409749

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.