Evidence map›Paper›PMID 34472500›Full record

ArticleMedical gas research

A special oropharyngeal oxygenation device to facilitate apneic oxygenation in comparison to high flow oxygenation devices.

Wolfgang A Wetsch, Daniel C Schroeder, Simon-Richard Finke, David Sander, Hannes Ecker, Bernd W Böttiger, Holger Herff

Open access · hybridAbstract read
In one paragraph

Article in Medical gas research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Wolfgang A WetschUniversity of Cologne, Faculty of Medicine; University Hospital of Cologne, Department of Anesthesiology and Postoperative Intensive Care Medicine, Cologne, Germany.
Daniel C SchroederUniversity of Cologne, Faculty of Medicine; University Hospital of Cologne, Department of Anesthesiology and Postoperative Intensive Care Medicine, Cologne; Department of Anesthesiology and Intensive Care, German Armed Forces Central Hospital of Koblenz, Koblenz, Germany.
Simon-Richard FinkeUniversity of Cologne, Faculty of Medicine; University Hospital of Cologne, Department of Anesthesiology and Postoperative Intensive Care Medicine, Cologne, Germany.
David SanderUniversity of Cologne, Faculty of Medicine; University Hospital of Cologne, Department of Anesthesiology and Postoperative Intensive Care Medicine, Cologne, Germany.
Hannes EckerUniversity of Cologne, Faculty of Medicine; University Hospital of Cologne, Department of Anesthesiology and Postoperative Intensive Care Medicine, Cologne, Germany.
Bernd W BöttigerUniversity of Cologne, Faculty of Medicine; University Hospital of Cologne, Department of Anesthesiology and Postoperative Intensive Care Medicine, Cologne, Germany.
Holger HerffUniversity of Cologne, Faculty of Medicine; University Hospital of Cologne, Department of Anesthesiology and Postoperative Intensive Care Medicine, Cologne, Germany.
University Hospital Cologne · DEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oxygen application and apneic oxygenation may reduce the risk of hypoxemia due to apnea during awake fiberoptic intubation or failed endotracheal intubation. High flow devices are recommended, but their effect compared to moderate deep oropharyngeal oxygen application is unknown. Designed as an experimental manikin trial, we made a comparison between oxygen application via nasal prongs at 10 L/min (control group), applying oxygen via oropharyngeal oxygenation device (at 10 L/min), oxygen application via high flow nasal oxygen with 20 L/min and 90% oxygen (20 L/90% group), oxygen application via high flow nasal oxygen with 60 L/min and 45% oxygen (60 L/45% group), and oxygen application via sealed face mask with a special adapter to allow for fiberoptic entering of the airway. We preoxygenated the lung of a manikin and measured the decrease in oxygen level during the following 20 minutes for each way of oxygen application. Oxygen levels fell from 97 ± 1% at baseline to 75 ± 1% in control group, and to 86 ± 1% in oropharyngeal oxygenation device group. In the high flow nasal oxygen group, oxygen level dropped to 72 ± 1% in the 20 L/90% group and to 44 ± 1% in the 60 L/45% group. Oxygen level remained at 98 ± 0% in the face mask group. In conclusion, in this manikin simulation study of apneic oxygenation, oxygen insufflation using a sealed face mask kept oxygen levels in the test lung at 98% over 20 minutes, oral oxygenation device led to oxygen levels at 86%, whereas all other methods resulted in the decrease of oxygen levels below 75%.

Indexed as

ApneaIntubation, IntratrachealHumansLungManikinsOxygen Inhalation TherapyRespiration, Artificialairway managementapneic oxygenationHFNOhigh flow nasal oxygenintubationnasal oxygenoxygentracheal intubation

Identifiers

PMID34472500
PMCPMC8447949
OpenAlexW3191720577

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.