Evidence map›Paper›PMID 34472499›Full record

ArticleMedical gas research

Xenon as a transdermal enhancer for niacinamide in Strat-M™ membranes.

Evgeny Petrov, Alexander Verkhovskiy

Open access · hybridAbstract read
In one paragraph

Article in Medical gas research. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Evgeny PetrovLaboratory of Biochemistry of Transport Systems, Faculty of Innovative Technologies, National Research Tomsk State University, Tomsk, Russian Federation.
Alexander VerkhovskiyLaboratory of Biochemistry of Transport Systems, Faculty of Innovative Technologies, National Research Tomsk State University, Tomsk, Russian Federation.
National Research Tomsk State University · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Xenon is confirmed to diffuse readily through membranes and has properties of transdermal enhancer. In this study, the ability of xenon to regulate the transdermal diffusion of niacinamide was investigated using a model of an artificial skin analogue of Strat-M™ membranes in Franz cells. Based on the data obtained, we found that in the simplified biophysical model of Strat-M™ membranes xenon exerts its enhancer effect based on the heterogeneous nucleation of xenon at the interfaces in the microporous structures of Strat-M™ membranes.

Indexed as

SkinSkin AbsorptionMembranes, ArtificialNiacinamideXenonMembranes, ArtificialNiacinamideXenonenhancerFranz cellgas nucleationniacinamidepermeationskinStrat-Mtransdermal drug delivery systemxenon

Identifiers

PMID34472499
PMCPMC8447954
OpenAlexW3193700504

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.