ArticleJournal of the American Heart Association2021
Impact of Social Frailty in Hospitalized Elderly Patients With Heart Failure: A FRAGILE-HF Registry Subanalysis.
Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.
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Who cites it
26 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.
- Social frailty as a predictor of all-cause mortality and functional disability: a systematic review and meta-analysis.Scientific reports · 2024Pooled it
- Frailty and Recurrent Hospitalization in Older Vietnamese Adults with Heart Failure: A Prospective Cohort Study.Annals of geriatric medicine and research · 2026Article
- Social frailty and mortality risk in middle-aged and older adults: a prospective cohort study.GeroScience · 2026Article
- Social Frailty in Heart Failure: Concept, Impact and Preventive Strategies.Journal of advanced nursing · 2026Review
- Prognostic Value of Frailty Assessment Combining the Frailty Index Based on Laboratory Tests With the Clinical Frailty Scale in Patients With Acute Heart Failure.Journal of the American Heart Association · 2025Observational
- Social Determinants of Health and 30-Day Readmission for Heart Failure Patients in U.S. Hospitals: Evidence from ICD-10 Z-Code Data.Healthcare (Basel, Switzerland) · 2025Article
- Prognostic impact of multi-domain approaches and the Tilburg frailty indicator in elderly patients with heart failure.Aging clinical and experimental research · 2025Article
- Frailty determinants in heart failure: Inflammatory markers, cognitive impairment and psychosocial interaction.ESC heart failure · 2025Article
- Association between social frailty and quality of life in older patients with chronic heart failure: sequential multiple mediating effects of family insufficiency and social networks.Frontiers in medicine · 2025Article
- Analysis of influencing factors and paths of social frailty in older adult patients with ischemic stroke: a cross-sectional study.Frontiers in public health · 2025Article
- Prognostic Value of Objective Social Isolation and Loneliness in Older Patients With Heart Failure: Subanalysis of FRAGILE-HF and Kitasato Cohort.Journal of the American Heart Association · 2024Article
- Prognostic impact of MitraScore in elderly Asian patients with heart failure: sub-analysis of FRAGILE-HF.ESC heart failure · 2024Article
- Frailty and heart failure: State-of-the-art review.Journal of cachexia, sarcopenia and muscle · 2023Review
- Relationship between the spread of COVID-19, social frailty, and depressive symptoms in patients with heart failure.Heart and vessels · 2023Article
- Prognostic effects of cardiac rehabilitation in heart failure patients classified according to physical frailty: A propensity score-matched analysis of a nationwide prospective cohort study.International journal of cardiology. Cardiovascular risk and prevention · 2023Article
- Frailty and caregiver relationship quality in older patients diagnosed with transthyretin cardiac amyloidosis.Aging clinical and experimental research · 2023Article
- Mortality Risks after Two Years in Frail and Pre-Frail Older Adults Admitted to Hospital.Journal of clinical medicine · 2023Article
- Prevalence and Impact of Social Frailty in Patients with Chronic Obstructive Pulmonary Disease.International journal of chronic obstructive pulmonary disease · 2023Article
- Analysis of the status of social frailty in Chinese older adults with cardiovascular and cerebrovascular diseases: a national cross-sectional study.Frontiers in public health · 2023Article
- Social Frailty and Meaningful Activities among Community-Dwelling Older Adults with Heart Disease.International journal of environmental research and public health · 2022Article
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Authors and funding
22 authors at 14 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background Frailty is conceptualized as an accumulation of deficits in multiple areas and is strongly associated with the prognosis of heart failure (HF). However, the social domain of frailty is less well investigated. We prospectively evaluated the clinical characteristics and prognostic impact of social frailty (SF) in elderly patients with HF. Methods and Results FRAGILE-HF (prevalence and prognostic value of physical and social frailty in geriatric patients hospitalized for heart failure) is a multicenter, prospective cohort study focusing on patients hospitalized for HF and aged ≥65 years. We defined SF by Makizako's 5 items, which have been validated as associated with future disability. The primary end point was a composite of all-cause death and rehospitalization because of HF. The impact of SF on all-cause mortality alone was also evaluated. Among 1240 enrolled patients, 825 (66.5%) had SF. During the 1-year observation period after discharge, the rates of the combined end point and all-cause mortality were significantly higher in patients with SF than in those without SF (Log-rank test: both
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