Evidence map›Paper›PMID 34472114›Full record

ArticleThe International journal of eating disorders2021

Clinical moderators and predictors of cognitive-behavioral therapy by guided-self-help versus therapist-led for binge-eating disorder: Analysis of aggregated clinical trials.

Carlos M Grilo, Heather Thompson-Brenner, Rebecca M Shingleton, Douglas R Thompson, Debra L Franko

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The International journal of eating disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

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  8. Binge eating disorder.Nature reviews. Disease primers · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Carlos M GriloDepartment of Psychiatry, Yale University School of Medicine, New Haven, Connecticut, USA.ORCID 0000-0003-0245-3444
Heather Thompson-BrennerDepartment of Psychology, Boston University, Boston, Massachusetts, USA.
Rebecca M ShingletonDepartment of Psychology, Boston University, Boston, Massachusetts, USA.
Douglas R ThompsonThompson Research Consulting, Chicago, Illinois, USA.
Debra L FrankoDepartment of Applied Psychology, Northeastern University, Boston, Massachusetts, USA.
Boston University · USChicago Public Schools · USNortheastern University · USYale University · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Treatment of Obesity and Binge Eating: Behavioral weight Loss versus Stepped CareR01DK049587 · NIDDK · YALE UNIVERSITY · PI GRILO, CARLOS M · 2002 to 2020
$8.5M
Treatment Response in Ethnic Minority Individuals With Binge Eating DisorderR03MH083987 · NIMH · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI THOMPSON-BRENNER, HEATHER · 2009 to 2010
$176k
NCATS NIH HHS UL1 TR001863NIDDK NIH HHS R01 DK049587NIMH NIH HHS R03 MH083987
6 · The paper itself

Abstract

objectiveCognitive-behavioral therapy (CBT)-therapist-led (CBTth) and guided-self-help (CBTgsh)-has efficacy for binge-eating disorder (BED) but many patients do not benefit sufficiently. We examined predictors and moderators for these two CBT methods.

methodData were aggregated from randomized controlled trials (RCTs) testing psychosocial treatments for BED in the U.S. Predictors and moderators of outcomes (treatment completion and binge-eating remission) were examined in N = 457 participants who received either CBTgsh (N = 164) or CBTth (N = 293).

resultsAnalyses, adjusting for demographic/clinical variables, indicated CBTth was significantly superior to CBTgsh for treatment completion (odds ratio [OR] = 20.0) and remission (OR = 14.6). For remission, analyses revealed significant predictors (age, treatment length, Weight Concern), a moderator (weight concern [OR = 5.13]), and a significant interaction between CBT-type and treatment length (OR = 2.66). For CBTgsh, longer treatment was associated with less remission, whereas for CBTth, longer treatment was associated with greater remission. For CBTgsh, 44.1% with low weight concern versus 56.3% with high weight concern achieved remission whereas for CBTth, 43.5% with high weight concern and 61.0% with low weight concern achieved remission. DISCUSSION: Analyses of aggregated RCT BED data, adjusting for demographic/clinical characteristics, indicated superiority (large effect-sizes) in treatment outcomes of CBTth over CBTgsh and that Weight Concern moderated outcomes.

Indexed as

Binge-Eating DisorderBulimiaCognitive Behavioral TherapyHealth BehaviorHumansTreatment Outcomebinge-eating disordercognitive-behavior therapyeating disordersguided self-helpmoderatorspredictorstreatment

Identifiers

PMID34472114
PMCPMC8492524
OpenAlexW3196573222

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.