Evidence map›Paper›PMID 34472036›Full record

ArticleWorld journal of pediatrics : WJP2021

Role of ultrasound in the diagnosis of cervical tuberculous lymphadenitis in children.

Tian-Zhuo Yu, Ying Zhang, Wen-Zhi Zhang, Gao-Yi Yang

Open access · hybridAbstract read
In one paragraph

Article in World journal of pediatrics : WJP, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Tian-Zhuo YuDepartment of Ultrasonography, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, Chinese and Western Hospital of Zhejiang Province (Hangzhou Red Cross Hospital), No. 208 Huancheng East Road, Hangzhou, 310003, China.
Ying ZhangDepartment of Ultrasonography, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, Chinese and Western Hospital of Zhejiang Province (Hangzhou Red Cross Hospital), No. 208 Huancheng East Road, Hangzhou, 310003, China.
Wen-Zhi ZhangDepartment of Ultrasonography, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, Chinese and Western Hospital of Zhejiang Province (Hangzhou Red Cross Hospital), No. 208 Huancheng East Road, Hangzhou, 310003, China.
Gao-Yi YangDepartment of Ultrasonography, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, Chinese and Western Hospital of Zhejiang Province (Hangzhou Red Cross Hospital), No. 208 Huancheng East Road, Hangzhou, 310003, China. yanggaoyi8@163.com.ORCID http://orcid.org/0000-0002-0759-3684
Hangzhou Red Cross Hospital · CN

Funding

Agriculture and Social development Plan of Hangzhou 20190101A09Medical Science and Technology Project of Zhejiang Province 2019KY513Medical Science and Technology Project of Zhejiang Province 2020KY732Science and Technology Plan of Hangzhou 20180533B68
6 · The paper itself

Abstract

backgroundTo describe sonographic characteristics of cervical tuberculous lymphadenitis (CTBL) in children, clinical information, and sonograms of 348 lymph nodes (LNs) from 57 children with CTBL were retrospectively analyzed in this study.

methodsWe retrospectively reviewed the clinical data and sonograms of 348 LNs from 31 boys and 26 girls with CTBL, who were confirmed by pathology or laboratory examination, at the Hangzhou Red Cross Hospital between June 2014 and December 2020. The age of the children ranged from 1 to 14 years (average 7.1 ± 2.9 years).

resultsNight sweats, fatigue and loss of appetite were the most common clinical symptoms observed in children with CTBL. Unilateral LN involvements were common. Occasionally, CTBL was found in healthy children with no symptoms. On sonography, the hilus was absent or unclear in all LNs. The short-to-long axis (S/L) ratio was ≥ 0.5, and the edges were unclear in most LNs. Other accompanying findings included necrosis (47.4%), an echogenic thin layer (36.8%), surrounding soft-tissue edema (38.5%), multiple intra-nodal strong echo (28.2%), sinus (22.7%) and abscess formation (6.9%). The Doppler ultrasound showed that the majority of vascularity patterns of CTBL were capsular or peripheral (33.3%).

conclusionsUltrasound is a recommended examination method for children from different age groups with cervical lymphadenitis. The ultrasonic signs of hilus absence, S/L ratio ≥ 0.5, unclear edge, necrosis, echogenic thin layer, strong echoes and capsular or peripheral vascularity may aid in the diagnosis of cervical tuberculous lymphadenitis.

Indexed as

Tuberculosis, Lymph NodeAdolescentChildChild, PreschoolDiagnosis, DifferentialFemaleHumansInfantLymph NodesMaleRetrospective StudiesUltrasonographyCervical lymphadenitisChildrenTuberculosisUltrasonography

Identifiers

PMID34472036
PMCPMC8523381
OpenAlexW3196842355

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.