Evidence map›Paper›PMID 34472020›Full record

Trial reportJournal of general internal medicine2022

Effect of Personalized Messages Sent by a Health System's Patient Portal on Influenza Vaccination Rates: a Randomized Clinical Trial.

Peter G Szilagyi, Christina S Albertin, Alejandra Casillas, Rebecca Valderrama, O Kenrik Duru, Michael K Ong, Sitaram Vangala, Chi-Hong Tseng, Sharon G Humiston, Sharon Evans and 4 more

Registry-linked trialAbstract readRandomized Controlled TrialPragmatic Clinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Journal of general internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04110314 (Improving Influenza Vaccination Delivery Across a Health System by the Electronic Health Records Patient Portal- RCT #2), which is not on this map. Cited by 15 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04110314 nacompletednot on this map

Improving Influenza Vaccination Delivery Across a Health System by the Electronic Health Records Patient Portal- RCT #2

TypeinterventionalSponsorUniversity of California, Los AngelesRan2019 to 2020Enrolled430,636ConditionsInfluenza, Respiratory Tract InfectionsArmsPortal Reminders for Influenza Vaccination: Gain-framed, Portal Reminders for Influenza Vaccination: Loss-framed, Pre-commitment prompt
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Peter G SzilagyiDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California at Los Angeles, Los Angeles, CA, USA. pszilagyi@mednet.ucla.edu.ORCID 0000-0003-1951-0644
Christina S AlbertinDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California at Los Angeles, Los Angeles, CA, USA.
Alejandra CasillasDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Rebecca ValderramaDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California at Los Angeles, Los Angeles, CA, USA.
O Kenrik DuruDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Michael K OngDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Sitaram VangalaDepartment of Medicine Statistics Core, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Chi-Hong TsengDepartment of Medicine Statistics Core, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Sharon G HumistonDepartment of Pediatrics, Children's Mercy, Kansas City, MO, USA.
Sharon EvansDepartment of Information Services and Solutions, UCLA Health System, Los Angeles, CA, USA.
Michael SloyanDepartment of Information Services and Solutions, UCLA Health System, Los Angeles, CA, USA.
Jonathan E BogardUCLA Anderson School of Management, Los Angeles, CA, USA.
Craig R FoxDepartment of Medicine, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.
Carlos LernerDepartment of Pediatrics, UCLA Mattel Children's Hospital, University of California at Los Angeles, Los Angeles, CA, USA.

Funding

Improving Influenza Vaccination Delivery Across a Health System by the Electronic Health Records Patient PortalR01AI135029 · NIAID · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI SZILAGYI, PETER G · 2018 to 2022
$3.7M
NIAID NIH HHS 1R01AI135029-01NIAID NIH HHS R01 AI135029
6 · The paper itself

Abstract

backgroundAdult influenza vaccination rates are low. Tailored patient reminders might raise rates.

objectiveEvaluate impact of a health system's patient portal reminders: (1) tailored to patient characteristics and (2) incorporating behavioral science strategies, on influenza vaccination rates among adults.

designPragmatic 6-arm randomized trial across a health system during the 2019-2020 influenza vaccination season. The setting was one large health system-53 adult primary care practices.

participantsAll adult patients who used the patient portal within 12 months, stratified by the following: young adults (18-64 years, without diabetes), older adults (≥65 years, without diabetes), and those with diabetes (≥18 years).

interventionsPatients were randomized within strata to either (1) pre-commitment reminder alone (1 message, mid-October), (2) pre-commitment + loss frame messages, (3) pre-commitment + gain frame messages, (4) loss frame messages alone, (5) gain frame messages alone, or (6) standard of care control. Patients in the pre-commitment group were sent a message in mid-October, asking if they planned on getting an influenza vaccination. Patients in loss or gain frame groups were sent up to 3 portal reminders (late October, November, and December, if no documented influenza vaccination in the EHR) about importance and safety of influenza vaccine. MAIN MEASURES: Receipt of 1 influenza vaccine from 10/01/2019 to 03/31/2020. KEY

results196,486 patients (145,166 young adults, 29,795 older adults, 21,525 adults with diabetes) were randomized. Influenza vaccination rates were as follows: for young adults 36.8%, for older adults 55.6%, and for diabetics 60.6%. On unadjusted and adjusted (for age, gender, insurance, race, ethnicity, and prior influenza vaccine history) analyses, influenza vaccination rates were not statistically different for any study group versus control.

conclusionsPatient reminders sent by a health system's patient portal that were tailored to patient demographics (young adults, older adults, diabetes) and that incorporated two behavioral economic messaging strategies (pre-commitment and loss/gain framing) were not effective in raising influenza vaccination rates.

trial registrationThis trial was registered with ClinicalTrials.gov (NCT04110314).

Indexed as

Influenza, HumanInfluenza VaccinesPatient PortalsText MessagingAgedHumansReminder SystemsVaccinationYoung AdultInfluenza Vaccines

Identifiers

PMID34472020
PMCPMC8858355

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.