Evidence map›Paper›PMID 34471938›Full record

ArticleIntensive care medicine2021

Cytokine adsorption in severe, refractory septic shock.

Pedro David Wendel Garcia, Matthias Peter Hilty, Ulrike Held, Eva-Maria Kleinert, Marco Maggiorini

Registry-linked trialAbstract readLetter
In one paragraph

Article in Intensive care medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06145828 (Clinical Application of Cytokine Adsorption Technology in AIDS Patients With Severe Pneumonia and/or Septic Shock), which is not on this map. Cited by 43 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
43citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06145828 recruitingnot on this mapstarted 2023, after this paper: background citation

Clinical Application of Cytokine Adsorption Technology in AIDS Patients With Severe Pneumonia and/or Septic Shock: An Observational Study.

TypeobservationalSponsorGuangzhou 8th People's HospitalRan2023 to 2027Enrolled60ConditionsAIDS Pneumonia, Septic ShockArmsCytokine Adsorption
3 · Its place in the literature

Who cites it

43 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Hemoadsorption in septic shock - CON.Intensive care medicine · 2025
    Article
  13. Review
  14. Article
  15. A few words of caution on blood purification in sepsis.Critical care (London, England) · 2025
    Article
  16. Article
  17. Review
  18. Article
  19. Macrophage activation syndrome in Sepsis: from pathogenesis to clinical management.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Review
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Pedro David Wendel GarciaInstitute of Intensive Care Medicine, University Hospital of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.ORCID http://orcid.org/0000-0001-7775-3279
Matthias Peter HiltyInstitute of Intensive Care Medicine, University Hospital of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-2765-881X
Ulrike HeldDepartment of Biostatistics and Epidemiology, Biostatistics and Prevention Institute, University of Zürich, Zurich, Switzerland.ORCID http://orcid.org/0000-0003-3105-5840
Eva-Maria KleinertInstitute of Intensive Care Medicine, University Hospital of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland.
Marco MaggioriniInstitute of Intensive Care Medicine, University Hospital of Zurich, Rämistrasse 100, 8091, Zurich, Switzerland. klinmax@usz.uzh.ch.ORCID http://orcid.org/0000-0001-8180-2117

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

HemoperfusionShockShock, SepticAdsorptionCytokinesHumansCytokines

Identifiers

PMID34471938
PMCPMC8409473

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.