Evidence map›Paper›PMID 34471853›Full record

ReviewBioelectricity2020

Toward Closed-Loop Electrical Stimulation of Neuronal Systems: A Review.

Jarno M A Tanskanen, Annika Ahtiainen, Jari A K Hyttinen

Open access · hybridAbstract readReview
In one paragraph

Review in Bioelectricity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Multifunctional bioelectronics for brain-body circuits.Nature reviews bioengineering · 2025
    Article
  3. Article
  4. Review
  5. Computational Neurosurgery in Deep Brain Stimulation.Advances in experimental medicine and biology · 2024
    Review
  6. Review
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Jarno M A TanskanenBioMediTech Institute and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Annika AhtiainenBioMediTech Institute and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Jari A K HyttinenBioMediTech Institute and Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Tampere University · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Biological neuronal cells communicate using neurochemistry and electrical signals. The same phenomena also allow us to probe and manipulate neuronal systems and communicate with them. Neuronal system malfunctions cause a multitude of symptoms and functional deficiencies that can be assessed and sometimes alleviated by electrical stimulation. Our working hypothesis is that real-time closed-loop full-duplex measurement and stimulation paradigms can provide more in-depth insight into neuronal networks and enhance our capability to control diseases of the nervous system. In this study, we review extracellular electrical stimulation methods used in

Indexed as

brainclosed-loopelectrical stimulationneuronal cellsneuronal stimulationopen-loop

Identifiers

PMID34471853
PMCPMC8370352
OpenAlexW3095425716

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.