Evidence map›Paper›PMID 34471750›Full record

ArticleACS omega2021

Degradation-Dependent Controlled Delivery of Doxorubicin by Glyoxal Cross-Linked Magnetic and Porous Chitosan Microspheres.

Nechikkottil Sivadasan Sumitha, Prabha Prakash, Balagopal N Nair, Gopalakrishnanchettiar Sivakamiammal Sailaja

Open access · goldAbstract read
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 25 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Hydrogel Microparticles for Bone Regeneration.Gels (Basel, Switzerland) · 2023
    Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Nechikkottil Sivadasan SumithaDepartment of Polymer Science and Rubber Technology, Cochin University of Science and Technology, Kochi 682 022, Kerala, India.
Prabha PrakashDepartment of Biotechnology, Cochin University of Science and Technology, Kochi 682 022, Kerala, India.
Balagopal N NairSchool of Molecular and Life Sciences (MLS), Faculty of Science and Engineering, Curtin University, GPO Box U1987, Perth WA6845, Australia.
Gopalakrishnanchettiar Sivakamiammal SailajaDepartment of Polymer Science and Rubber Technology, Cochin University of Science and Technology, Kochi 682 022, Kerala, India.ORCID https://orcid.org/0000-0002-6406-7293
Cochin University of Science and Technology · INCurtin University · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glyoxal cross-linked porous magnetic chitosan microspheres, GMS (∼170 μm size), with a tunable degradation profile were synthesized by a water-in-oil emulsion technique to accomplish controlled delivery of doxorubicin (DOX), a chemotherapeutic drug, to ensure prolonged chemotherapeutic effects. The GMS exhibit superparamagnetism with saturation magnetization,

Identifiers

PMID34471750
PMCPMC8388080
OpenAlexW3189703611

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.