Evidence map›Paper›PMID 34471571›Full record

ArticleCureus2021

Comparison of Genicular Nerve Block in Combination With Adductor Canal Block in Both Primary and Revision Total Knee Arthroplasty: A Retrospective Case Series.

Promil Kukreja, Alana Venter, Lauren Mason, Alexander M Kofskey, Theresa Northern, Sameer Naranje, Elie Ghanem, Prentiss A Lawson, Hari Kalagara

3 registry-linked trialsAbstract read
In one paragraph

Article in Cureus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06065878 nacompletednot on this mapstarted 2022, after this paper: background citation

Comparison Of The Analgesic Efficacy Of IPACK (Interspace Between The Popliteal Artery And Capsule Of The Posterior Knee) Block Alone And IPACK Block Combined With Genicular Block In Patients Planned For Total Knee Arthroplasty

TypeinterventionalSponsorCenk GacemerRan2022 to 2023Enrolled40ConditionsPain, Joint, Knee Arthropathy, Anesthesia, Orthopedic DisorderArmsIPACK + Genicular Nerve Block
NCT06864663 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Comparative Study of Combined Ultrasound-Guided Adductor Canal Block and Interspace Between the Popliteal Artery and Capsule of the Knee (IPACK) Versus Combined Adductor Canal Block and Genicular Nerve Block Following Total Knee Arthroplasty

TypeinterventionalSponsorAin Shams UniversityRan2025 to 2025Enrolled70ConditionsNerve Block, Regional AnaesthesiaArmsnerve block with bupivacaine 0.25%, Nerve Block with bupivacaine 0.25%
NCT07478783 nacompletednot on this map

Addition Of Genicular Nerve Block To Femoral Nerve Block Improves Early Postoperative Analgesia After Total Knee Replacement: A Randomized Controlled Trial

TypeinterventionalSponsorAnkara City Hospital BilkentRan2021 to 2022Enrolled80ConditionsTotal Knee AnthroplastyArmsUltrasound-guided Femoral Nerve Block, ltrasound-guided Genicular Nerve Block
3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Promil KukrejaAnesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, USA.
Alana VenterAnesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, USA.
Lauren MasonMedicine, Edward Via College of Osteopathic Medicine, Birmingham, USA.
Alexander M KofskeyMedicine, University of Alabama at Birmingham School of Medicine, Birmingham, USA.
Theresa NorthernAnesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, USA.
Sameer NaranjeDepartment of Orthopaedic Surgery, University of Alabama at Birmingham, Birmingham, USA.
Elie GhanemDepartment of Orthopaedic Surgery, University of Alabama at Birmingham, Birmingham, USA.
Prentiss A LawsonAnesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, USA.
Hari KalagaraAnesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The management of pain in patients undergoing total knee arthroplasty (TKA) for chronic knee osteoarthritis (OA) has remained a challenge for the anesthesiologist regarding regional anesthesia as no single regional technique is adequate with regard to balancing effective analgesia with minimal muscle weakness. Severe postoperative pain following TKA has been shown to negatively impact patient outcomes and mortality. The genicular nerve block has recently been demonstrated to provide effective analgesia to the anterior and posterior knee capsule in recent studies. In this retrospective case series, we compare the efficacy of combined genicular nerve block (GNB) and adductor canal block (ACB) to only ACB in both primary and revision TKA patients. This combined novel approach for TKA patients can be utilized to improve patient pain scores and early ambulation, limiting the use of opioids and early discharge.

Indexed as

adductor canal blockgenicular nerve blockoral morphine equivalentspost-operative analgesiatotal knee arthroplasty

Identifiers

PMID34471571
PMCPMC8399964

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.