ReviewClinical kidney journal2021
Kidney involvement in multisystem inflammatory syndrome in children: a pediatric nephrologist's perspective.
Review in Clinical kidney journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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Who cites it
15 citing papers in PubMed.
- Acute kidney injury in critically ill children: Incidence, severity, and clinical outcomes from a quaternary pediatric intensive care unit in an upper-middle-income country.Pediatric nephrology (Berlin, Germany) · 2026Article
- Comparative study of post- COVID-19 Kawasaki disease and multisystem inflammatory syndrome cases at Alexandria University Children's Hospital.BMC pediatrics · 2026Article
- Acute Kidney Injury in Children: A Focus for the General Pediatrician.Children (Basel, Switzerland) · 2024Review
- Acute kidney injury in children with moderate-severe COVID-19 and multisystem inflammatory syndrome in children: a referral center experience.Pediatric nephrology (Berlin, Germany) · 2024Article
- A retrospective analysis of acute kidney injury in children with post-COVID-19 multisystem inflammatory syndrome: insights into promising outcomes.Italian journal of pediatrics · 2024Article
- Editorial on the Special Issue "Advances in Pediatric Acute Kidney Injury".Children (Basel, Switzerland) · 2024Article
- Renal Involvement in Multisystem Inflammatory Syndrome in Children: Not Only Acute Kidney Injury.Children (Basel, Switzerland) · 2023Article
- Case Report: Multisystem inflammatory syndrome in children with associated proximal tubular injury.Frontiers in nephrology · 2023Article
- Update on the treatment of multisystem inflammatory syndrome in children associated with COVID-19.Future virology · 2022Review
- Clinical presentation and short-term outcomes of multisystemic inflammatory syndrome in children in Lagos, Nigeria during the COVID-19 pandemic: A case series.EClinicalMedicine · 2022Article
- Six-month multidisciplinary follow-up in multisystem inflammatory syndrome in children: An Italian single-center experience.Frontiers in pediatrics · 2022Article
- Are we losing awareness of other infections due to the fear of coronavirus disease-2019 and MIS-C?Germs · 2021Article
- An 11-Year-Old Saudi Arabian Girl Who Presented with Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with SARS-CoV-2 Infection with Coronary Artery Aneurysm and Cardiac Involvement: A Case Report.The American journal of case reports · 2021Article
- Hematuria as an Early Sign of Multisystem Inflammatory Syndrome in Children: A Case Report of a Boy With Multiple Comorbidities and Review of Literature.Frontiers in pediatrics · 2021Article
- A Tale of Two Pathologies: MIS-C in a Patient with Pediatric Systemic Lupus Erythematosus.Indian journal of nephrologyArticle
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The initial report of the multisystem inflammatory syndrome in children (MIS-C) was from the UK in April 2020; since then, cases have been reported worldwide. Renal involvement has been seen commonly, ranging from 10% to 46%. Kidney involvement following severe acute respiratory syndrome coronavirus 2 infection in children with MIS-C is more common than initially thought and is associated with higher morbidity and mortality. There are several reports of a direct viral tropism of coronavirus disease 2019 and MIS-C-associated renal damage. This study's objective was to systematically review the current understanding of kidney involvement in children suffering from MIS-C. Based on our systemic literature search, 19 studies have either partially or fully discussed kidney involvement in MIS-C patients. Furthermore, we discuss the multifactorial pathogenesis contributing to acute kidney injury (AKI) development in MIS-C. The current review gives a pediatric nephrologist's perspective of the renal involvement in MIS-C, the incidence of AKI, the pathophysiology of AKI in MIS-C and the proposed therapeutic regimens available, including the need for kidney replacement therapy for a child with AKI associated with MIS-C. As the disease is rapidly evolving, more detailed clinical prospective studies are required to understand MIS-C and its role in AKI better.
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