ArticleUpsala journal of medical sciences2021
Validation of the diagnosis of eosinophilic esophagitis based on histopathology reports in Sweden.
Article in Upsala journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.
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Who cites it
13 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.
- Systematic Review: Variability in Definitions of Fibrostenosis in Eosinophilic Oesophagitis.Alimentary pharmacology & therapeutics · 2025Pooled it
- Eosinophilic Esophagitis and Autoimmune Thyroid Disease: A Population-Based Matched Cohort Study.United European gastroenterology journal · 2026Article
- Risk of asthma in individuals with eosinophilic esophagitis: Population-based cohort study with sibling analyses.Clinical and translational allergy · 2025Article
- Cohort Update: ESPRESSO (Epidemiology Strengthened by Histopathology Reports in Sweden).Clinical epidemiology · 2025Article
- Risk of Cancer Diagnosis in Patients With Eosinophilic Esophagitis Using a Nationwide Swedish Population Cohort.United European gastroenterology journal · 2024Article
- Association of celiac disease with eosinophilic esophagitis: Nationwide register-based cohort study with sibling analyses.The journal of allergy and clinical immunology. Global · 2024Article
- Eosinophilic esophagitis: Current concepts in diagnosis and management.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2024Review
- Eosinophilic esophagitis and risk of incident major adverse cardiovascular events: a nationwide matched cohort study.Esophagus : official journal of the Japan Esophageal Society · 2024Article
- Eosinophilic esophagitis is associated with increased risk of later inflammatory bowel disease in a nationwide Swedish population cohort.United European gastroenterology journal · 2024Article
- Pregnancy Outcomes in Females with Eosinophilic Esophagitis: A Nationwide Population-Based Study.Inflammatory intestinal diseases · 2023Article
- Prior hospital-based infection and risk of eosinophilic esophagitis in a Swedish nationwide case-control study.United European gastroenterology journal · 2022Article
- Risk of fractures in individuals with eosinophilic esophagitis: nationwide population-based cohort study.Esophagus : official journal of the Japan Esophageal Society · 2022Article
- Mortality in Eosinophilic Esophagitis - a nationwide, population-based matched cohort study from 2005 to 2017.Upsala journal of medical sciences · 2021Article
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Authors and funding
5 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEosinophilic esophagitis (EoE) is a relatively new diagnosis, where until recently a specific international classification of disease code was missing. One way to identify patients with EoE is to use histopathology codes. We validated the clinicopathological EoE diagnosis based on histopathology reports and patient charts to establish these data sources as the basis for a nationwide EoE patient cohort.
methodsThrough the Epidemiology Strengthened by histoPathology Reports in Sweden (ESPRESSO) study, we randomly selected 165 patients from five Swedish health care regions with a histopathologic diagnosis of EoE. Patients were assigned a histopathology diagnosis of EoE if they had ≥15 eosinophils per high-power field or, in the absence of eosinophil quantification, the pathologist interpreted the biopsy as consistent with EoE. Patient charts were scrutinized to see if the other diagnostic criteria were fulfilled. Of the 131 received patient charts, 111 (85%) had sufficient information to be included in the study.
resultsOf the 111 validated patients, 99 had EoE, corresponding to a positive predictive value of 89% (95% confidence interval = 82-94%). Dysphagia was the most common symptom (
conclusionHistopathology reports from the ESPRESSO cohort with esophageal eosinophilic inflammation are suggestive of EoE.
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