Evidence map›Paper›PMID 34471401›Full record

ArticleDose-response : a publication of International Hormesis Society

Determination of the Median Effective Dose of Dexmedetomidine for the Prevention of Emergence Agitation in Geriatric Patients Undergoing Major Open Surgery With General Anesthesia: A Prospective, Double-Blinded, Dose-Response Trial.

WeiBing Wang, Hui Zhou, AiJiao Sun, JinBo Xiao, JingChong Dong, Huang Xu

Abstract read
In one paragraph

Article in Dose-response : a publication of International Hormesis Society. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

WeiBing WangDepartment of Anesthesiology, The Affiliated AnQing Municipal Hospitals of Anhui Medical University, AnQing, China.ORCID https://orcid.org/0000-0002-6059-7916
Hui ZhouDepartment of Anesthesiology, The Affiliated AnQing Municipal Hospitals of Anhui Medical University, AnQing, China.
AiJiao SunDepartment of Anesthesiology, The Affiliated AnQing Municipal Hospitals of Anhui Medical University, AnQing, China.
JinBo XiaoDepartment of Anesthesiology, The Affiliated AnQing Municipal Hospitals of Anhui Medical University, AnQing, China.
JingChong DongDepartment of Anesthesiology, The Affiliated AnQing Municipal Hospitals of Anhui Medical University, AnQing, China.
Huang XuDepartment of Anesthesiology, The Affiliated AnQing Municipal Hospitals of Anhui Medical University, AnQing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dexmedetomidine can effectively decrease the incidences of emergence agitation (EA) in adult patients, but there are major side effects related to increased dose of dexmedetomidine. The purpose of this study was to determine the median effective dose of dexmedetomidine in the prevention of EA among geriatric patients undergoing major open surgery with general anesthesia. A total of 50 geriatric patients were enrolled in this study. Dexmedetomidine 0.5 μg·kg

Indexed as

dexmedetomidineemergence agitationgeriatricmedian effective dose

Identifiers

PMID34471401
PMCPMC8404654

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.