Evidence map›Paper›PMID 34471383›Full record

ReviewCancer management and research2021

Ibero-American Expert Consensus on Squamous Cell Carcinoma of the Head and Neck Treatment in Patients Unable to Receive Cisplatin: Recommendations for Clinical Practice.

Agustín Falco, Thiago Bueno de Oliveira, Jon Cacicedo, Aylen Vanessa Ospina, Miguel Ángel Ticona, Héctor Galindo, Marcos David Pereira, José Luis Aguilar-Ponce, Antonio Rueda-Domínguez, Tannia Soria and 5 more

Open access · goldAbstract readReview
In one paragraph

Review in Cancer management and research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 12 institutions in 8 countries.

Agustín FalcoInstituto Alexander Fleming, Asociación Argentina de Oncología Clínica (AAOC), Buenos Aires, Argentina.
Thiago Bueno de OliveiraAC Camargo Cancer Center, Sociedade Brasileira de Oncologia Clínica (SBOC), São Paulo, Brazil.ORCID 0000-0002-6472-3596
Jon CacicedoHospital Universitario Cruces/Biocruces Bizkaia Health Research Institute, Barakaldo, Bizkaia, Spain.
Aylen Vanessa OspinaICCAL, Hospital Universitario Fundación Santa Fe de Bogotá, Asociación Colombiana de Hematología y Oncología (ACHO), Bogotá, Colombia.
Miguel Ángel TiconaHospital Nacional Edgardo Rebagliati Martins de Lima, Sociedad Peruana de Oncología Médica (SPOM), Lima, Perú.
Héctor GalindoPontificia Universidad Católica de Chile, Sociedad Chilena de Oncología Médica (SCOM), Santiago, Chile.
Marcos David PereiraInstituto de Oncología Ángel H. Roffo, Asociación Argentina de Oncología Clínica (AAOC), Buenos Aires, Argentina.
José Luis Aguilar-PonceInstituto Nacional de Cancerología, Sociedad Mexicana de Oncología (SMeO), Mexico City, Mexico.
Antonio Rueda-DomínguezUGC Oncología Médica, Hospital Universitario Regional y Virgen de la Victoria, IBIMA, Málaga, Spain.
Tannia SoriaHospital SOLCA de Quito, Sociedad Ecuatoriana de Oncología (SEO), Quito, Ecuador.
Miren TabernaInstitut Català d'Oncologia, ICO L'Hospitalet, Barcelona, Spain.
Lara IglesiasHospital 12 de Octubre, Madrid, Spain.
Taysser SowleyInstituto Oncológico Nacional (ION) de Panamá, Sociedad Panameña de Oncología (SPO), Panama City, Panama.
Ricard MesíaInstitut Català d'Oncologia, ICO Badalona, Barcelona, Spain.ORCID 0000-0002-3785-3563
TTCC group (Spanish Group for the Treatment of the Head and Neck Cancer)
Institut Català d'Oncologia · ESAC Camargo Hospital · BRBioCruces Health research Institute · ESFundación Santa Fe de Bogotá · COHospital Clínico Universitario Virgen de la Victoria · ESHospital Vozandes · ECInstituto Alexander Fleming · ARInstituto de Oncología de Rosario · ARInstituto Nacional de Cancerología · MXNational Oncologic Institute · PAPontificia Universidad Católica de Chile · CLResearch Institute Hospital 12 de Octubre · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cisplatin is the standard of treatment for squamous cell carcinoma of the head and neck (SCCHN) that has demonstrated efficacy, either in locally advanced disease when combined with radiotherapy at high doses, or in metastatic/recurrent disease when combined with other agents. However, the usual toxicities related to cisplatin, such as neurotoxicity, nephrotoxicity, ototoxicity, and hematologic toxicities, especially when high doses have been administered, have important implications in the patients' quality of life. The decision to administer cisplatin depends on several patient factors, such as age, performance status, weight loss, comorbidities, previous toxicities, chronic viral infection, or even the current SARS-CoV-2 pandemic. In order to establish recommendations for the management of patients with SCCHN, a group of experts in medical and radiation oncology from Spain and Latin-American discussed how to identify patients who are not candidates for cisplatin to offer them the most suitable therapeutic alternative.

Indexed as

agecisplatincomorbiditiescontraindicationfrailtytoxicity

Identifiers

PMID34471383
PMCPMC8405157
OpenAlexW3194057208

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.