Evidence map›Paper›PMID 34471362›Full record

ArticleInfection and drug resistance2021

Infective Endocarditis Caused by Extended-Spectrum Beta-Lactamase-Producing

Tsuneaki Kenzaka, Yuto Shinkura, Shizuo Kayama, Liansheng Yu, Sayoko Kawakami, Motoyuki Sugai, Satoru Kawasaki

Open access · goldAbstract readCase Reports
In one paragraph

Article in Infection and drug resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 68% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. IDCases · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Tsuneaki KenzakaDepartment of Internal Medicine, Hyogo Prefectural Tamba Medical Center, Tanba, Japan.ORCID 0000-0002-3120-6605
Yuto ShinkuraDepartment of Internal Medicine, Hyogo Prefectural Tamba Medical Center, Tanba, Japan.
Shizuo KayamaAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Liansheng YuAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Sayoko KawakamiAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Motoyuki SugaiAntimicrobial Resistance Research Center, National Institute of Infectious Diseases, Tokyo, Japan.
Satoru KawasakiDepartment of Internal Medicine, Hyogo Prefectural Tamba Medical Center, Tanba, Japan.
Hiroshima University · JPTokyo Metropolitan Tama-Hokubu Medical Center · JPNational Institute of Infectious Diseases · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionExtended-spectrum β-lactamase-producing CASE: An 83-year-old Japanese man who underwent mitral annuloplasty for mitral valve prolapse 5 years ago developed a fever of 38.5°C. The patient was hospitalized the first time for pyelonephritis and bacteremia due to ESBL-EC and treated successfully with the antimicrobial meropenem for 14 days. Two days after discharge, however, the patient was re-admitted with bacteremia due to ESBL-EC. He was treated successfully with the antimicrobial cefmetazole for 14 days. The patient was admitted to our institution for a third time due to bacteremia again, a day after discharge following meropenem antibiotic therapy. Transesophageal echocardiography showed vegetation in the anterior mitral valve annulus. Magnetic resonance imaging of the head showed septic cerebral embolism. The patient was diagnosed with infective endocarditis due to ESBL-EC and underwent mitral valve replacement. After 6 weeks of antibiotic therapy with meropenem and tobramycin, the patient recovered completely. The causative

conclusionOnly six cases of infective endocarditis associated with ESBL-EC have been reported in the past. Moreover, this is the first report of a patient with infective endocarditis bacteriologically or genetically analyzed for ESBL-EC. In future, factors that may cause infective endocarditis in ESBL-EC infections may be clarified through more thorough bacteriological/genetic analyses of ESBL-EC.

Indexed as

bacteremiablaCTX-M-27 ESBLE. coliinfective endocarditismeropenemST131

Identifiers

PMID34471362
PMCPMC8403558
OpenAlexW3195212102

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.