Evidence map›Paper›PMID 34471354›Full record

ArticleInternational journal of nanomedicine2021

Determination of Antioxidant Activity by Oxygen Radical Absorbance Capacity (ORAC-FL), Cellular Antioxidant Activity (CAA), Electrochemical and Microbiological Analyses of Silver Nanoparticles Using the Aqueous Leaf Extract of

Fernanda Pilaquinga, Jeroni Morey, Lenys Fernandez, Patricio Espinoza-Montero, Mauricio Moncada-Basualto, Josue Pozo-Martinez, Claudio Olea-Azar, Rafael Bosch, Lorena Meneses, Alexis Debut and 1 more

Abstract read
In one paragraph

Article in International journal of nanomedicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Probiotic Characteristics ofMicroorganisms · 2023
    Article
  6. Article
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Fernanda PilaquingaSchool of Chemical Sciences, Pontificia Universidad Católica del Ecuador, Quito, Ecuador.ORCID 0000-0002-0841-6313
Jeroni MoreyDepartment of Chemistry, University of the Balearic Islands, Palma de Mallorca, Spain.
Lenys FernandezSchool of Chemical Sciences, Pontificia Universidad Católica del Ecuador, Quito, Ecuador.
Patricio Espinoza-MonteroSchool of Chemical Sciences, Pontificia Universidad Católica del Ecuador, Quito, Ecuador.ORCID 0000-0003-0592-8652
Mauricio Moncada-BasualtoDepartment of Inorganic and Analytical Chemistry, University of Chile, Santiago, Chile.
Josue Pozo-MartinezDepartment of Inorganic and Analytical Chemistry, University of Chile, Santiago, Chile.
Claudio Olea-AzarDepartment of Inorganic and Analytical Chemistry, University of Chile, Santiago, Chile.
Rafael BoschEnvironmental Microbiology, IMEDEA (CSIC-UIB), and Microbiology, Department of Biology, University of Balearic Islands, Palma de Mallorca, Spain.
Lorena MenesesSchool of Chemical Sciences, Pontificia Universidad Católica del Ecuador, Quito, Ecuador.
Alexis DebutCentro de Nanociencia y Nanotecnología, Universidad de las Fuerzas Armadas ESPE, Sangolquí, Ecuador.
María de Las Nieves PiñaDepartment of Chemistry, University of the Balearic Islands, Palma de Mallorca, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe importance of studying polyphenolic compounds as natural antioxidants has encouraged the search for new methods of analysis that are quick and simple. The synthesis of silver nanoparticles (AgNPs) using plant extracts has been presented as an alternative to determine the total polyphenolic content and its antioxidant activity.

methodsIn this study, aqueous leaf extract of

resultsThe average size of nanoparticles was 5.2 ± 2.3 nm measured by high-resolution transmission electron microscopy (HR-TEM). The antioxidant activity measured by ORAC-FL in the extract and nanoparticles were 3944 ± 112 and 637.5 ± 14.8 µM ET/g of sample, respectively. Cellular antioxidant activity was 14.7 ± 0.2 for the aqueous extract and 12.5 ± 0.2 for the nanoparticles. The electrochemical index (EI) was 402 μA/V for the extract and 324 μA/V for the nanoparticles. Total polyphenolic content was 826.6 ± 20.9 and 139.7 ± 20.9 mg EGA/100 g of sample. Gallic acid was the main polyphenolic compound present in the leaf extract. Microbiological analysis revealed that although leaf extract was not toxic for

conclusionIt is concluded that the aqueous extract of the leaves of

Indexed as

Metal NanoparticlesSolanumAntioxidantsFluoresceinOxygen Radical Absorbance CapacityPlant ExtractsReactive Oxygen SpeciesSilverWaterAntioxidantsFluoresceinPlant ExtractsReactive Oxygen SpeciesSilverWaterantioxidant activityORACsilver nanoparticlesSolanum mammosumvoltammetry

Identifiers

PMID34471354
PMCPMC8405165

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.