ArticleMagnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine2022
Review of Quantitative Knee Articular Cartilage MR Imaging.
Article in Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed, 42 citations in OpenAlex.
- Healthy knee cartilage T2 mapping assessed with GRAPPATINI and multi-echo spin-echo (MESE) at 3T: regional values, longitudinal repeatability and method agreement.Quantitative imaging in medicine and surgery · 2026Article
- Multimodal model integrating ultrasound and demographic data for the diagnosis of knee osteoarthritis.BMC medical imaging · 2026Article
- Quantifying knee cartilage development trajectories in children aged 6-12 years via diffusion tensor imaging.Frontiers in pediatrics · 2026Article
- HSGDNet: Hybrid Synthetic-Data-Guided Deep Learning With NLS Refinement for Fast Multi-Component T1ρ Knee Mapping.NMR in biomedicine · 2025Article
- The Role ofBiomolecules · 2025Review
- A novel MRI contrast agent NaGdFScientific reports · 2025Article
- Magnetisation transfer, T1 and T2* relaxation in canine menisci of elderly dogs-anFrontiers in veterinary science · 2025Article
- Quantitative magnetic resonance imaging of paraspinal muscles for assessing chronic non-specific low back pain in young adults: a prospective case-control study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Gaining Insight into Updated MR Imaging for Quantitative Assessment of Cartilage Injury in Knee Osteoarthritis.Current rheumatology reports · 2024Review
- Factors influencing diffusion tensor imaging of knee cartilage in children ages 6-12 years: a prospective study.Pediatric radiology · 2024Article
- Sodium fluoride PET/CT with arthrography for cartilage evaluation of the knee.Radiology case reports · 2024Article
- Intra-articular administration of PLGA resveratrol sustained-release nanoparticles attenuates the development of rat osteoarthritis.Materials today. Bio · 2024Article
- Knowledge mapping and bibliometric analysis of medical knee magnetic resonance imaging for knee osteoarthritis (2004-2023).Frontiers in surgery · 2024Article
- Optimizing variable flip angles in magnetization-prepared gradient-echo sequences for efficient 3D-T1ρ mapping.Magnetic resonance in medicine · 2023Article
- T1ρ and T2* Measurements in Small and Knee-Sized Magnetic Resonance Imaging Phantoms: Effect of Phantom Size and Position Relative to Isocenter.Osteoarthritis imaging · 2023Article
- Artificial intelligence in knee osteoarthritis: A comprehensive review for 2022.Osteoarthritis imaging · 2023Article
- Meniscal allograft transplantation in discoid meniscus patients achieves good clinical outcomes and superior chondroprotection compared to meniscectomy in the long term.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2023Article
- Histological Findings and T2 Relaxation Time in Canine Menisci of Elderly Dogs-An Ex Vivo Study in Stifle Joints.Veterinary sciences · 2023Article
- Advanced MR Imaging for Knee Osteoarthritis: A Review on Local and Brain Effects.Diagnostics (Basel, Switzerland) · 2022Review
- Novel Magnetic Resonance Imaging Tools for the Diagnosis of Degenerative Disc Disease: A Narrative Review.Diagnostics (Basel, Switzerland) · 2022Review
Corrections and comments
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Authors and funding
4 authors at 3 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Osteoarthritis (OA) is one of the most prevalent disorders in today's society, resulting in significant socio-economic costs and morbidity. MRI is widely used as a non-invasive imaging tool for OA of the knee. However, conventional knee MRI has limitations to detect subtle early cartilage degeneration before morphological changes are visually apparent. Novel MRI pulse sequences for cartilage assessment have recently received increased attention due to newly developed compositional MRI techniques, including: T2 mapping, T1rho mapping, delayed gadolinium-enhanced MRI of cartilage (dGEMRIC), sodium MRI, diffusion-weighted imaging (DWI)/ diffusion tensor imaging (DTI), ultrashort TE (uTE), and glycosaminoglycan specific chemical exchange saturation transfer (gagCEST) imaging. In this article, we will first review these quantitative assessments. Then, we will discuss the variations of quantitative values of knee articular cartilage with cartilage layer (depth)- and angle (regional)-dependent approaches. Multiple MRI sequence techniques can discern qualitative differences in knee cartilage. Normal articular hyaline cartilage has a zonal variation in T2 relaxation times with increasing T2 values from the subchondral bone to the articular surface. T1rho values were also higher in the superficial layer than in the deep layer in most locations in the medial and lateral femoral condyles, including the weight-bearing portion. Magic angle effect on T2 mapping is clearly observed in the both medial and lateral femoral condyles, especially within the deep layers. One of the limitations for clinical use of these compositional assessments is a long scan time. Recent new approaches with compressed sensing (CS) and MR fingerprinting (MRF) have potential to provide accurate and fast quantitative cartilage assessments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.